software . 2020

Predicting protein intrinsically disordered regions by applying NLP practices

Chakraborty, Rajkumar; Yasha Hasija;
English
  • Published: 01 Jan 2020
  • Publisher: Code Ocean
Abstract
Protein intrinsically disorder regions lacks stable structure formations. this regions have found to play an important role in protein-protein interaction and protein-ligand interaction. mutations in these regions are also associated with various disease and alteration in drug metabolism. While these regions can be experimentally deduced using X-ray crystallography and NMR spectroscopy, but these experiments require high end instrument and time-intensive. therefore computational techniques can be used for prediction of these regions which are in-sillico and requires less time. In this work the IDRs are obtained from highly annotated databases and trained in an e...
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free text keywords: Capsule, Bioinformatics, protein intrinsic disorders, CNNs, LSTMs, Neural network, Natural Language processing, IDR Prediction
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Software . 2020
Provider: Datacite
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