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Emerging Infectious Diseases
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Emerging Infectious Diseases
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Asymptomatic Dengue Virus Infections, Cambodia, 2012–2013

Authors: Sowath Ly; Camille Fortas; Veasna Duong; Tarik Benmarhnia; Anavaj Sakuntabhai; Richard Paul; Rekol Huy; +11 Authors

Asymptomatic Dengue Virus Infections, Cambodia, 2012–2013

Abstract

We investigated dengue virus (DENV) and asymptomatic DENV infections in rural villages of Kampong Cham Province, Cambodia, during 2012 and 2013. We conducted perifocal investigations in and around households for 149 DENV index cases identified through hospital and village surveillance. We tested participants 0.5–30 years of age by using nonstructural 1 rapid tests and confirmed DENV infections using quantitative reverse transcription PCR or nonstructural 1–capture ELISA. We used multivariable Poisson regressions to explore links between participants’ DENV infection status and household characteristics. Of 7,960 study participants, 346 (4.4%) were infected with DENV, among whom 302 (87.3%) were <15 years of age and 225 (65.0%) were <9 years of age. We identified 26 (7.5%) participants with strictly asymptomatic DENV infection at diagnosis and during follow-up. We linked symptomatic DENV infection status to familial relationships with index cases. During the 2-year study, we saw fewer asymptomatic DENV infections than expected based on the literature.

International audience

Countries
France, United States
Subjects by Vocabulary

Library of Congress Subject Headings: lcsh:Medicine lcsh:Infectious and parasitic diseases lcsh:RC109-216 lcsh:R

Microsoft Academic Graph classification: Dengue virus medicine.disease_cause medicine.symptom Asymptomatic medicine business.industry Virology business

Keywords

Male, History, Epidemiology, vector-borne infections, Asymptomatic Dengue Virus Infections, Cambodia, 2012–2013, Infectious and parasitic diseases, RC109-216, Disease Outbreaks, Dengue, Aedes aegypti, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, risk factors, Mass Screening, Public Health Surveillance, Child, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, R, Age Factors, Aedes albopictus, 21st Century, Infectious Diseases, Medical Microbiology, Child, Preschool, Public Health and Health Services, Medicine, epidemiology, Female, Cambodia, Adult, Microbiology (medical), Asia, Adolescent, Clinical Sciences, Microbiology, History, 21st Century, Young Adult, asymptomatic, Humans, viruses, Preschool, mosquitoes, Mekong, dengue virus, Research, Asymptomatic Diseases, incidence, Sentinel Surveillance

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  • citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    21
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
21
Top 10%
Average
Top 10%
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