project . 2017 - 2022 . On going

ORTHOUNION

ORTHOpedic randomized clinical trial with expanded bone marrow MSC and bioceramics versus autograft in long bone nonUNIONs
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 733288 Call for proposal: H2020-SC1-2016-RTD
  • Funded under: H2020 | RIA Overall Budget: 5,999,150 EURFunder Contribution: 5,999,150 EUR
  • Status: On going
  • Start Date
    01 Jan 2017
    End Date
    30 Jun 2022
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Current orthopaedic treatments permit spontaneous bone regeneration to unite and heal 90% bone injuries. Non-union associates pain and disability, often requiring biological enhancement. Regenerative medicine research suggests to the general public that alternative treatments based on advanced therapy medicinal products (ATMP) are already available. However, early clinical trials only explore its potential benefit. Underreported results and absence of early trial confirmation in adequately powered prospective randomized clinical trials (RCT) indicate that evidence is not available to transfer any technique into routine clinical application. This ORTHOUNION Proje...
Description
Current orthopaedic treatments permit spontaneous bone regeneration to unite and heal 90% bone injuries. Non-union associates pain and disability, often requiring biological enhancement. Regenerative medicine research suggests to the general public that alternative treatments based on advanced therapy medicinal products (ATMP) are already available. However, early clinical trials only explore its potential benefit. Underreported results and absence of early trial confirmation in adequately powered prospective randomized clinical trials (RCT) indicate that evidence is not available to transfer any technique into routine clinical application. This ORTHOUNION Proje...
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