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The genetic prehistory of southern Africa
descriptionPublicationkeyboard_double_arrow_right Article 2012 United States, United States, France Publisher:Springer Science and Business Media LLCFunded by:NIH | Population mixture in evo..., NIH | African Odyssey: An Integ..., NSF | Collaborative Research: G... +2 projects
NIH| Population mixture in evolutionary and medical genetics ,
NIH| African Odyssey: An Integrative Genomics Analysis of Complex Physiologic Traits ,
NSF| Collaborative Research: Genetic Bases for the Evolution of Human Diet ,
NIH| Variation at Malaria Resistance Genes in Africans ,
NSF| A new history and geography of human genes informed by ancient DNA
Authors: Joseph K. Pickrell; Nick Patterson; Chiara Barbieri; Falko Berthold; +17 Authors
Joseph K. Pickrell; Nick Patterson; Chiara Barbieri; Falko Berthold; Linda Gerlach; Tom Güldemann; Blesswell Kure; Sununguko Wata Mpoloka; Hirosi Nakagawa; Christfried Naumann; Mark Lipson; Po-Ru Loh; Joseph Lachance; Joanna L. Mountain; Carlos Bustamante; Bonnie Berger; Sarah A. Tishkoff; Brenna M. Henn; Mark Stoneking; David Reich; Brigitte Pakendorf;
doi: 10.1038/ncomms2140 , 10.48550/arxiv.1207.5552
pmid: 23072811
pmc: PMC3493647
handle: 11858/00-001M-0000-002A-0ED0-6 , 11858/00-001M-0000-002A-0ED2-2 , 11858/00-001M-0000-000E-78FB-6 , 11858/00-001M-0000-000E-7818-4
doi: 10.1038/ncomms2140 , 10.48550/arxiv.1207.5552
pmid: 23072811
pmc: PMC3493647
handle: 11858/00-001M-0000-002A-0ED0-6 , 11858/00-001M-0000-002A-0ED2-2 , 11858/00-001M-0000-000E-78FB-6 , 11858/00-001M-0000-000E-7818-4
Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their relationships are poorly understood. Here, we report data from 23 populations analyzed at over half a million single nucleotide polymorphisms, using a genome-wide array designed for studying human history. The southern African Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeastern Kalahari, which we show separated within the last 30,000 years. We find that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began approximately 1,200 years ago. In addition, the east African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa To appear in Nature Communications
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The genetic prehistory of southern Africa
descriptionPublicationkeyboard_double_arrow_right Article 2012 United States, United States, France Publisher:Springer Science and Business Media LLCFunded by:NIH | Population mixture in evo..., NIH | African Odyssey: An Integ..., NSF | Collaborative Research: G... +2 projects
NIH| Population mixture in evolutionary and medical genetics ,
NIH| African Odyssey: An Integrative Genomics Analysis of Complex Physiologic Traits ,
NSF| Collaborative Research: Genetic Bases for the Evolution of Human Diet ,
NIH| Variation at Malaria Resistance Genes in Africans ,
NSF| A new history and geography of human genes informed by ancient DNA
Authors: Joseph K. Pickrell; Nick Patterson; Chiara Barbieri; Falko Berthold; +17 Authors
Joseph K. Pickrell; Nick Patterson; Chiara Barbieri; Falko Berthold; Linda Gerlach; Tom Güldemann; Blesswell Kure; Sununguko Wata Mpoloka; Hirosi Nakagawa; Christfried Naumann; Mark Lipson; Po-Ru Loh; Joseph Lachance; Joanna L. Mountain; Carlos Bustamante; Bonnie Berger; Sarah A. Tishkoff; Brenna M. Henn; Mark Stoneking; David Reich; Brigitte Pakendorf;
doi: 10.1038/ncomms2140 , 10.48550/arxiv.1207.5552
pmid: 23072811
pmc: PMC3493647
handle: 11858/00-001M-0000-002A-0ED0-6 , 11858/00-001M-0000-002A-0ED2-2 , 11858/00-001M-0000-000E-78FB-6 , 11858/00-001M-0000-000E-7818-4
doi: 10.1038/ncomms2140 , 10.48550/arxiv.1207.5552
pmid: 23072811
pmc: PMC3493647
handle: 11858/00-001M-0000-002A-0ED0-6 , 11858/00-001M-0000-002A-0ED2-2 , 11858/00-001M-0000-000E-78FB-6 , 11858/00-001M-0000-000E-7818-4
Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their relationships are poorly understood. Here, we report data from 23 populations analyzed at over half a million single nucleotide polymorphisms, using a genome-wide array designed for studying human history. The southern African Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeastern Kalahari, which we show separated within the last 30,000 years. We find that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began approximately 1,200 years ago. In addition, the east African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa To appear in Nature Communications
downloaddonwloadFull-Text
HAL-Inserm; Mémoires...arrow_drop_down
HAL-Inserm; Mémoires en Sciences de l'Information et de la Communication; HAL Lumiere Lyon 2; Hyper Article en Ligne - Sciences de l'Homme et de la Société; Hal-Diderot
Article . 2012
Full-Text: https://hal.univ-lyon2.fr/hal-01998848/document
Data sources: HAL-Inserm; Mémoires en Sciences de l'Information et de la Communication; HAL Lumiere Lyon 2; Hyper Article en Ligne - Sciences de l'Homme et de la Société; Hal-Diderot
Europe PubMed Central
Article . 2012
Full-Text: http://europepmc.org/articles/PMC3493647
Data sources: PubMed Central
Nature Communications
Article . 2012 . Peer-reviewed
License: CC BY NC SA
Data sources: Crossref
arXiv.org e-Print Archive
Other literature type . Preprint . 2012
Data sources: arXiv.org e-Print Archive
MPG.PuRe
Article . 2012
License: CC BY
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eScholarship - University of California
Article . 2012
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MPG.PuRe
Article . 2012
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MPG.PuRe
Article . 2012
Data sources: MPG.PuRe
DSpace@MIT
Article . 2012
License: CC BY NC SA
Data sources: DSpace@MIT
Nature Communications
Article
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MPG.PuRe
Article . 2012
Data sources: MPG.PuRe
https://doi.org/10.48550/arxiv...
Article . 2012
License: arXiv Non-Exclusive Distribution
Data sources: Datacite
https://pubmed.ncbi.nlm.nih.go...
Article . 2012
Data sources: Europe PubMed Central
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Access Routes
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247
citations 247
popularity Top 1%
influence Top 10%
impulse Top 1%
Powered by BIP!
more_vert
downloaddonwloadFull-Text
HAL-Inserm; Mémoires...arrow_drop_down
HAL-Inserm; Mémoires en Sciences de l'Information et de la Communication; HAL Lumiere Lyon 2; Hyper Article en Ligne - Sciences de l'Homme et de la Société; Hal-Diderot
Article . 2012
Full-Text: https://hal.univ-lyon2.fr/hal-01998848/document
Data sources: HAL-Inserm; Mémoires en Sciences de l'Information et de la Communication; HAL Lumiere Lyon 2; Hyper Article en Ligne - Sciences de l'Homme et de la Société; Hal-Diderot
Europe PubMed Central
Article . 2012
Full-Text: http://europepmc.org/articles/PMC3493647
Data sources: PubMed Central
Nature Communications
Article . 2012 . Peer-reviewed
License: CC BY NC SA
Data sources: Crossref
arXiv.org e-Print Archive
Other literature type . Preprint . 2012
Data sources: arXiv.org e-Print Archive
MPG.PuRe
Article . 2012
License: CC BY
Data sources: MPG.PuRe
eScholarship - University of California
Article . 2012
Data sources: eScholarship - University of California
MPG.PuRe
Article . 2012
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MPG.PuRe
Article . 2012
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DSpace@MIT
Article . 2012
License: CC BY NC SA
Data sources: DSpace@MIT
Nature Communications
Article
License: CC BY ND SA
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MPG.PuRe
Article . 2012
Data sources: MPG.PuRe
https://doi.org/10.48550/arxiv...
Article . 2012
License: arXiv Non-Exclusive Distribution
Data sources: Datacite
https://pubmed.ncbi.nlm.nih.go...
Article . 2012
Data sources: Europe PubMed Central
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citeCite
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Digital Humanities and Cultural Heritage
Publications
National Science Foundation
African Odyssey: An Integrative Gen...