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Accelerator-produced radioisotopes are widely used in modern medicine, for imaging, for cancer therapy, and for combinations of therapy and diagnostics. Clinical trials are well advanced for several radioisotope-based treatments that might open the way to a strong request of specific accelerator systems dedicated to radioisotope production. While cyclotrons are the standard tool in this domain, we explore here alternative options using linear accelerators. Compared to cyclotrons, linacs have the advantage of modularity, compactness, and reduced beam loss with lower shielding requirements. Although in general more expensive than cyclotrons, linacs are competitive in cost for production of low-energy proton beams, or of intense beams of heavier particles. After a review of radioisotopes of potential interest, in particular those produced with low-energy protons or helium, this paper presents two linac-based isotope production systems. The first is a compact RFQ-based system for PET isotopes, and the second is an alpha-particle linac for production of alpha-emitters. The accelerator systems are described, together with calculations of production yields for different targets. Proceedings of the 13th International Particle Accelerator Conference, IPAC2022, Bangkok, Thailand

Abstract Using a thin Nb layer on Copper substrate has several advantages compared with the bulk Nb in construction of Superconducting Radiofrequency accelerating cavities (SRF) for particle accelerators. We were evaluating the properties of two series of Nb layers deposited on Cu substrate, mainly by determining the start of magnetic flux penetration into the sample – the first magnetic flux entry field B en, proportional to the B c1. The values of B en are compared with the surface roughness and surface morphology of the Nb layers, which have a strong influence on B en. The surfaces of the samples were also treated by Nd:YAG laser depending on laser irradiation dose. The results of B en and surface roughness before and after laser polishing are compared.

The ever-expanding requirements of high-power targets and accelerator equipment has highlighted the need for facilities capable of accommodating experiments with a diverse range of objectives. HiRadMat, a High Radiation to Materials testing facility at CERN has, throughout operation, established itself as a global user facility capable of going beyond its initial design goals. Pulsed high energy, high intensity, proton beams have been delivered to experiments ranging from materials testing, detector’s prototype validation, radiation to electronics assessment and beam instrumentation. A 440 GeV/c proton beam is provided directly from the CERN SPS. Up to 288 bunches/pulse at a maximum pulse intensity of 3.5 x 10¹³ protons/pulse can be delivered. Through collaborative efforts, HiRadMat has developed into a state-of-the-art facility with improved in situ measurement routines, beam diagnostic systems and data acquisition techniques, offered to all users. This contribution summarises the recent experimental achievements, highlights previous facility enhancements and discusses potential future upgrades with particular focus on HiRadMat as a facility open to novel experiments. Proceedings of the 10th Int. Particle Accelerator Conf., IPAC2019, Melbourne, Australia

MESA is a two pass energy recovery linac (ERL) currently under construction at the Johannes Gutenberg-University in Mainz. MESA uses four 1.3 GHz TESLA type cavities with 12.5 MV/m of accelerating gradient in two modified ELBE type cryomodule with improved thermal connection of the HOM antennas and cw operation. In the first stage of MESA operation 1mA of beam current is foreseen, which will later be upgraded to 10mA. One potential limit to maximum beam current in ERLs is the transverse beam breakup (BBU) instability induced by dipole Higher Order Modes (HOMs). These modes can be excited by bunches passing through the cavities off axis. Following bunches are then deflected by the HOMs, which results in even larger offsets for recirculated bunches. This feedback can even lead to beam loss. Simulation results for HOM spectra of a single TESLA cavity are available for example in *. It was possible to measure the HOM spectra in the cold, not tuned cavities at DESY and in the cold string tuned to the 1.3 GHz fundamental mode at Mainz. Results for the maximum beam current for MESA, limited by BBU, for the various HOM spectra are presented. Proceedings of the 10th Int. Particle Accelerator Conf., IPAC2019, Melbourne, Australia

Two new absorbing materials were developed as collimator inserts to fulfil the requirements of HL-LHC higher brightness beams: molybdenum-carbide graphite (MoGr) and copper-diamond (CuCD). These materials were tested under intense beam impacts at CERN HiRadMat facility in 2015, when full jaw prototypes were irradiated. Additional tests in HiRadMat were performed in 2017 on another series of material samples, including also improved grades of MoGr and CuCD, and different coating solutions. This paper summarizes the main results of the two experiments, with a main focus on the behaviour of the novel composite blocks, the metallic housing, as well as the cooling circuit. The experimental campaign confirmed the final choice for the materials and the design solutions for HL-LHC collimators, and constituted a unique chance of benchmarking numerical models. In particular, the tests validated the selection of MoGr for primary and secondary collimators, and CuCD as a valid solution for robust tertiary collimators. Proceedings of the 10th Int. Particle Accelerator Conf., IPAC2019, Melbourne, Australia

In this proceeding it is discussed the effect of coherent vs. incoherent effect and discussing the validity of frozen models of space charge according to the Debye length and beam radius. This in view of discussing the relation of IBS and space charge Proceedings of the 10th Int. Particle Accelerator Conf., IPAC2019, Melbourne, Australia

In view of the High-Luminosity upgrade of the Large Hadron Collider (LHC) collimation system, a family of novel molybdenum-carbide graphite (MoGr) composites was developed to meet the challenging requirements of HL-LHC beam-halo collimation, in particular the electrical conductivity and thermo-mechanical performances. The Ultra-High Vacuum (UHV) behaviour of this material was extensively characterized to assess its compatibility with the accelerator’s specifications. The results presented in this paper correlate the outgassing behaviour with the microscopic features of MoGr compared to other graphite-based materials. Residual gas analysis (RGA) was exploited to optimize post-production treatments. Proceedings of the 10th Int. Particle Accelerator Conf., IPAC2019, Melbourne, Australia