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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Laurens P.; Toma P.; Schoen A.; Daraio C.; +1 Authors

    This work explores the relationship between multinational R&D and innovation productivity among top corporate knowledge and R&D producers by adopting a twofold concept of internationalisation: (1) the firm’s degree of R&D internationalisation, and (2) the firm’s geographic diversification. We model the patent production process with an appropriate and robust conditional Data Envelopment Analysis (DEA) estimator, using a unique database of firms that matches financial indicators and patent information. Our results reinforce the fundamental role of internationalisation in the knowledge production process when the internationalisation process is properly and strategically managed. We interpret our empirical evidence through the theoretical lens of the learning theory of internationalisation, and we postulate that a high R&D intensity is a key driver to overcoming the challenges of internationalisation. International audience

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Quality & Quantity; ...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    HAL - UPEC / UPEM
    Article . 2022
    Data sources: HAL - UPEC / UPEM
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Kameda, Koichi; Kelly, Ann H; Lezaun, Javier; Löwy, Ilana;

    When the Zika virus burst onto the international scene in the second half of 2015, the development of diagnostic tools was seen as an urgent global health priority. Diagnostic capacity was restricted to a small number of reference laboratories, and none of the few available molecular or serological tests had been validated for extensive use in an outbreak setting. In the early weeks of the crisis, key funders stepped in to accelerate research and development efforts, and the WHO took responsibility for steering diagnostic standardization, a role it had successfully played during the West Africa Ebola virus outbreak. Yet when the WHO declared the end of the Zika Public Health Emergency of International Concern in November 2016, diagnostic capacity remained patchy, and few tools were available at the scale required in the countries that bore the brunt of the epidemic, particularly Brazil. This article analyses the limited impact of global R&D efforts on the availability of Zika diagnostic options where they were most needed and for those most vulnerable: women who might have been exposed to the virus during their pregnancy and children born with suspected congenital Zika syndrome. The truncated legacies of testing during the Zika crisis reveal some of the fault lines in the global health enterprise, particularly the limits of ‘emergency R&D’ to operate in geopolitical contexts that do not conform to the ideal type of a humanitarian crisis, or to tackle technical issues that are inextricably linked to domestic struggles over the scope and distribution of biological citizenship. Diagnostic shortcomings, we argue, lie at the heart of the stunning transformation, in less than two years, in the status of Zika: from international public health emergency to neglected disease. International audience

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Oxford University Re...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Social Studies of Science
    Article
    License: CC BY
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Jens Chluba; Maximilian H. Abitbol; Nabila Aghanim; Yacine Ali-Haïmoud; +26 Authors

    This Voyage 2050 paper highlights the unique science opportunities using spectral distortions of the cosmic microwave background (CMB). CMB spectral distortions probe many processes throughout the history of the Universe, delivering novel information that complements past, present and future efforts with CMB anisotropy and large-scale structure studies. Precision spectroscopy, possible with existing technology, would not only provide key tests for processes expected within the cosmological standard model but also open an enormous discovery space to new physics. This offers unique scientific opportunities for furthering our understanding of inflation, recombination, reionization and structure formation as well as dark matter and particle physics. A dedicated experimental approach could open this new window to the early Universe in the decades to come, allowing us to turn the long-standing upper distortion limits obtained with COBE/FIRAS some 25 years ago into clear detections of the expected standard distortion signals and also challenge our current understanding of the laws of nature. International audience

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Experimental Astrono...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    arXiv.org e-Print Archive
    Other literature type . Preprint . 2019
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Experimental Astronomy
    Article
    License: CC BY
    Data sources: UnpayWall
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    NARCIS
    Article . 2021
    Data sources: NARCIS
    https://doi.org/10.48550/arxiv...
    Article . 2019
    License: arXiv Non-Exclusive Distribution
    Data sources: Datacite
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Experimental Astrono...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      arXiv.org e-Print Archive
      Other literature type . Preprint . 2019
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Experimental Astronomy
      Article
      License: CC BY
      Data sources: UnpayWall
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      NARCIS
      Article . 2021
      Data sources: NARCIS
      https://doi.org/10.48550/arxiv...
      Article . 2019
      License: arXiv Non-Exclusive Distribution
      Data sources: Datacite
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Xavier Faïn; Rachael H. Rhodes; Philip Place; Vasilii V. Petrenko; +8 Authors

    Abstract. Carbon monoxide (CO) is a regulated pollutant and one of the key components determining the oxidizing capacity of the atmosphere. Obtaining a reliable record of atmospheric CO mixing ratios ([CO]) since preindustrial times is necessary to evaluate climate–chemistry models under conditions different from today and to constrain past CO sources. We present high-resolution measurements of CO mixing ratios from ice cores drilled at five different sites on the Greenland ice sheet that experience a range of snow accumulation rates, mean surface temperatures, and different chemical compositions. An optical-feedback cavity-enhanced absorption spectrometer (OF-CEAS) was coupled with continuous melter systems and operated during four analytical campaigns conducted between 2013 and 2019. Overall, continuous flow analysis (CFA) of CO was carried out on over 700 m of ice. The CFA-based CO measurements exhibit excellent external precision (ranging from 3.3 to 6.6 ppbv, 1σ) and achieve consistently low blanks (ranging from 4.1±1.2 to 12.6±4.4 ppbv), enabling paleoatmospheric interpretations. However, the five CO records all exhibit variability that is too large and rapid to reflect past atmospheric mixing ratio changes. Complementary tests conducted on discrete ice samples demonstrate that these variations are not artifacts of the analytical method (i.e., production of CO from organics in the ice during melting) but are very likely related to in situ CO production within the ice before analysis. Evaluation of the signal resolution and co-investigation of high-resolution records of CO and total organic carbon (TOC) suggest that past atmospheric CO variations can be extracted from the records' baselines with accumulation rates higher than 20 cm w.e.yr-1 (water equivalent per year). Consistent baseline CO records from four Greenland sites are combined to produce a multisite average ice core reconstruction of past atmospheric CO for the Northern Hemisphere high latitudes, covering the period from 1700 to 1957 CE. Such a reconstruction should be taken as an upper bound of past atmospheric CO abundance. From 1700 to 1875 CE, the record reveals stable or slightly increasing values in the 100–115 ppbv range. From 1875 to 1957 CE, the record indicates a monotonic increase from 114±4 to 147±6 ppbv. The ice core multisite CO record exhibits an excellent overlap with the atmospheric CO record from Greenland firn air which spans the 1950–2010 CE time period. The combined ice core and firn air CO history, spanning 1700–2010 CE, provides useful constraints for future model studies of atmospheric changes since the preindustrial period. International audience

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Climate of the Past ...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Climate of the Past (CP)
    Other literature type . 2021
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    https://doi.org/10.5194/cp-202...
    Preprint . 2021 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Climate of the Past (CP)
    Article . 2022 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    https://cp.copernicus.org/prep...
    Preprint
    License: CC BY
    Data sources: UnpayWall
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Climate of the Past
    Article . 2022
    Data sources: DOAJ
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Climate of the Past ...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Climate of the Past (CP)
      Other literature type . 2021
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      https://doi.org/10.5194/cp-202...
      Preprint . 2021 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Climate of the Past (CP)
      Article . 2022 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      https://cp.copernicus.org/prep...
      Preprint
      License: CC BY
      Data sources: UnpayWall
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Climate of the Past
      Article . 2022
      Data sources: DOAJ
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Casal, J.; Gómez-Ramos, M.; Moro, A.M.; Corsi, A.;

    The Transfer to the Continuum method has been applied to describe the 11Li(p, pn) and 14Be(p, pn) reactions in inverse kinematics, using structure overlaps computed within a full three-body model for the projectile. Calculations agree with the available experimental data on the unbound 10Li and 13Be nuclei. Ministerio de Ciencia, Innovación y Universidades FIS2017-88410-P, FPA2016-77689-C2-1-R European Union's Horizon 2020 654002

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Recolector de Cienci...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    arXiv.org e-Print Archive
    Other literature type . Preprint . 2019
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Journal of Physics : Conference Series
    Other literature type . Article . 2020 . Peer-reviewed
    License: CC BY
    https://doi.org/10.48550/arxiv...
    Article . 2019
    License: arXiv Non-Exclusive Distribution
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    Authors: Lorc��, C��dric;

    We review some of the recent developments regarding mass, angular momentum and pressure forces inside hadrons. These properties are all encoded in the energy-momentum tensor of the system, which is described at the non-perturbative level in terms of gravitational form factors. Similarly to electromagnetic form factors, Fourier transforms of gravitational form factors allow one to map out the distribution of the above mechanical properties in position space, providing a whole new way of studying in detail the internal structure of hadrons. 5 pages, 2 figures, contribution to the proceedings of the 27th International Nuclear Physics Conference (INPC) 2019, July 29- August 2, Glasgow, UK

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    Journal of Physics : Conference Series
    Article . 2020 . Peer-reviewed
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      Journal of Physics : Conference Series
      Article . 2020 . Peer-reviewed
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    Authors: Banks, William E.; Moncel, Marie-Helene; Raynal, J.P.; Cobos, MC; +7 Authors

    International audience; Abstract Middle Paleolithic Neanderthal populations occupied Eurasia for at least 250,000 years prior to the arrival of anatomically modern humans. While a considerable body of archaeological research has focused on Neanderthal material culture and subsistence strategies, little attention has been paid to the relationship between regionally specific cultural trajectories and their associated existing fundamental ecological niches, nor to how the latter varied across periods of climatic variability. We examine the Middle Paleolithic archaeological record of a naturally constrained region of Western Europe between 82,000 and 60,000 years ago using ecological niche modeling methods. Evaluations of ecological niche estimations, in both geographic and environmental dimensions, indicate that 70,000 years ago the range of suitable habitats exploited by these Neanderthal populations contracted and shifted. These ecological niche dynamics are the result of groups continuing to occupy habitual territories that were characterized by new environmental conditions during Marine Isotope Stage 4. The development of original cultural adaptations permitted this territorial stability.

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    Authors: Domingo-Pardo; C.; Babiano-Suarez; V.; +203 Authors

    The idea of slow-neutron capture nucleosynthesis formulated in 1957 triggered a tremendous experimental effort in different laboratories worldwide to measure the relevant nuclear physics input quantities, namely (n, γ) cross sections over the stellar temperature range (from few eV up to several hundred keV) for most of the isotopes involved from Fe up to Bi. A brief historical review focused on total energy detectors will be presented to illustrate how advances in instrumentation have led to the assessment of new aspects of s-process nucleosynthesis and to the progressive refinement of stellar models. A summary will be presented on current efforts to develop new detection concepts, such as the Total-Energy Detector with γ-ray imaging capability (i-TED). The latter is based on the simultaneous combination of Compton imaging with neutron time-of-flight (TOF) techniques, in order to achieve a superior level of sensitivity and selectivity in the measurement of stellar neutron capture rates. European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (ERC Consolidator Grant project HYMNS) 681740 Instituto de Salud Carlos III Spanish Government FPA2014-52823-C2-1-P FPA2017-83946-C2-1-P Consejo Superior de Investigaciones Cientificas (CSIC) PIE-201750I26 Program Severo Ochoa SEV-2014-0398

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    Other literature type . Preprint . 2019
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    Other literature type . 2020
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    ROBIS
    Article . 2020
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    https://doi.org/10.48550/arxiv...
    Article . 2019
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    Authors: Thibaud Saos; Sophie Grégoire; Jean-Jacques Bahain; Thomas Higham; +11 Authors

    This paper presents new archaeological material and first dates on Upper Pleistocene layers at the site of La Crouzade cave (Gruissan, Aude, France). The site was first excavated by T. and P. Héléna at the beginning of the twentieth century, and the excavations were recently completed during three years (2016–2018) of systematic campaigns. We obtained dates from Middle Palaeolithic layers using two methods: AMS 14C dates were obtained from bone and charcoal, and combined ESR-U series dating was undertaken on horse teeth. Together, these methods allowed us to date this Mousterian sequence to 49,776–44805 cal BP for the deepest level (layer C8) and from 42,000 ± 3000 years BP for the top (layer C6). The Upper Palaeolithic layers are preserved only as patches in the actual excavation area, but a date was obtained from a piece of charcoal collected from a small hearth preserved in the first layer (C5) above Middle Palaeolithic deposits, which indicates an age similar to that of a modern human maxillary previously analysed and re-dated here from 36,014 to 34402 cal BP, confirming its stratigraphic attribution. The Middle Palaeolithic lithics at the site were first described as para-Charentian cultural facies following typological analyses. The revision of the earlier collection supplemented with the new material, using a technological approach, allow to identify two layers dominated by Levallois production followed by discoid production (Layers C8 and C6) surrounding an original assemblage (layer C7), characterised by a dominant Levallois production completed by three secondary production systems of equal importance, including discoid, SSDA and a Quina-like production. The faunal spectrum predominantly comprises an assemblage of Pleistocene large mammals, and biochronological studies corroborate the dates obtained.

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    Authors: D.-D. Rousseau; D.-D. Rousseau; P. Antoine; N. Boers; +11 Authors

    The global character of the millennial-scale climate variability associated with the Dansgaard-Oeschger (DO) events in Greenland has been well-established for the last glacial cycle. Mainly due to the sparsity of reliable data, however, the spatial coherence of corresponding variability during the penultimate cycle is less clear. New investigations of European loess records from Marine Isotope Stage (MIS) 6 reveal the occurrence of alternating loess intervals and paleosols (incipient soil horizons), similar to those from the last climatic cycle. These paleosols are correlated, based on their stratigraphical position and numbers as well as available optically stimulated luminescence (OSL) dates, with in-terstadials described in various Northern Hemisphere records and in GLt_syn, the synthetic 800 kyr record of Greenland ice core δ 18 O. Therefore, referring to the interstadials described in the record of the last climate cycle in European loess sequences, the four MIS 6 interstadials can confidently be interpreted as DO-like events of the penultimate climate cycle. Six more interstadials are identified from proxy measurements performed on the same interval, leading to a total of 10 interstadials with a DO-like event status. The statistical similarity between the millennial-scale loess-paleosol oscillations during the last and penultimate climate cycle provides direct empirical evidence that the cycles of the penultimate cycle are indeed of the same nature as the DO cycles originally discovered for the last glacial cycle. Our results thus imply that their underlying cause and global imprint were characteristic of at least the last two climate cycles. International audience (IF 4.29; Q1)

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    Climate of the Past (CP)
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    Authors: Laurens P.; Toma P.; Schoen A.; Daraio C.; +1 Authors

    This work explores the relationship between multinational R&D and innovation productivity among top corporate knowledge and R&D producers by adopting a twofold concept of internationalisation: (1) the firm’s degree of R&D internationalisation, and (2) the firm’s geographic diversification. We model the patent production process with an appropriate and robust conditional Data Envelopment Analysis (DEA) estimator, using a unique database of firms that matches financial indicators and patent information. Our results reinforce the fundamental role of internationalisation in the knowledge production process when the internationalisation process is properly and strategically managed. We interpret our empirical evidence through the theoretical lens of the learning theory of internationalisation, and we postulate that a high R&D intensity is a key driver to overcoming the challenges of internationalisation. International audience

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    HAL - UPEC / UPEM
    Article . 2022
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    Authors: Kameda, Koichi; Kelly, Ann H; Lezaun, Javier; Löwy, Ilana;

    When the Zika virus burst onto the international scene in the second half of 2015, the development of diagnostic tools was seen as an urgent global health priority. Diagnostic capacity was restricted to a small number of reference laboratories, and none of the few available molecular or serological tests had been validated for extensive use in an outbreak setting. In the early weeks of the crisis, key funders stepped in to accelerate research and development efforts, and the WHO took responsibility for steering diagnostic standardization, a role it had successfully played during the West Africa Ebola virus outbreak. Yet when the WHO declared the end of the Zika Public Health Emergency of International Concern in November 2016, diagnostic capacity remained patchy, and few tools were available at the scale required in the countries that bore the brunt of the epidemic, particularly Brazil. This article analyses the limited impact of global R&D efforts on the availability of Zika diagnostic options where they were most needed and for those most vulnerable: women who might have been exposed to the virus during their pregnancy and children born with suspected congenital Zika syndrome. The truncated legacies of testing during the Zika crisis reveal some of the fault lines in the global health enterprise, particularly the limits of ‘emergency R&D’ to operate in geopolitical contexts that do not conform to the ideal type of a humanitarian crisis, or to tackle technical issues that are inextricably linked to domestic struggles over the scope and distribution of biological citizenship. Diagnostic shortcomings, we argue, lie at the heart of the stunning transformation, in less than two years, in the status of Zika: from international public health emergency to neglected disease. International audience

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    Social Studies of Science
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    Authors: Jens Chluba; Maximilian H. Abitbol; Nabila Aghanim; Yacine Ali-Haïmoud; +26 Authors

    This Voyage 2050 paper highlights the unique science opportunities using spectral distortions of the cosmic microwave background (CMB). CMB spectral distortions probe many processes throughout the history of the Universe, delivering novel information that complements past, present and future efforts with CMB anisotropy and large-scale structure studies. Precision spectroscopy, possible with existing technology, would not only provide key tests for processes expected within the cosmological standard model but also open an enormous discovery space to new physics. This offers unique scientific opportunities for furthering our understanding of inflation, recombination, reionization and structure formation as well as dark matter and particle physics. A dedicated experimental approach could open this new window to the early Universe in the decades to come, allowing us to turn the long-standing upper distortion limits obtained with COBE/FIRAS some 25 years ago into clear detections of the expected standard distortion signals and also challenge our current understanding of the laws of nature. International audience

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    Experimental Astronomy
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    https://doi.org/10.48550/arxiv...
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      Experimental Astronomy
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    Authors: Xavier Faïn; Rachael H. Rhodes; Philip Place; Vasilii V. Petrenko; +8 Authors

    Abstract. Carbon monoxide (CO) is a regulated pollutant and one of the key components determining the oxidizing capacity of the atmosphere. Obtaining a reliable record of atmospheric CO mixing ratios ([CO]) since preindustrial times is necessary to evaluate climate–chemistry models under conditions different from today and to constrain past CO sources. We present high-resolution measurements of CO mixing ratios from ice cores drilled at five different sites on the Greenland ice sheet that experience a range of snow accumulation rates, mean surface temperatures, and different chemical compositions. An optical-feedback cavity-enhanced absorption spectrometer (OF-CEAS) was coupled with continuous melter systems and operated during four analytical campaigns conducted between 2013 and 2019. Overall, continuous flow analysis (CFA) of CO was carried out on over 700 m of ice. The CFA-based CO measurements exhibit excellent external precision (ranging from 3.3 to 6.6 ppbv, 1σ) and achieve consistently low blanks (ranging from 4.1±1.2 to 12.6±4.4 ppbv), enabling paleoatmospheric interpretations. However, the five CO records all exhibit variability that is too large and rapid to reflect past atmospheric mixing ratio changes. Complementary tests conducted on discrete ice samples demonstrate that these variations are not artifacts of the analytical method (i.e., production of CO from organics in the ice during melting) but are very likely related to in situ CO production within the ice before analysis. Evaluation of the signal resolution and co-investigation of high-resolution records of CO and total organic carbon (TOC) suggest that past atmospheric CO variations can be extracted from the records' baselines with accumulation rates higher than 20 cm w.e.yr-1 (water equivalent per year). Consistent baseline CO records from four Greenland sites are combined to produce a multisite average ice core reconstruction of past atmospheric CO for the Northern Hemisphere high latitudes, covering the period from 1700 to 1957 CE. Such a reconstruction should be taken as an upper bound of past atmospheric CO abundance. From 1700 to 1875 CE, the record reveals stable or slightly increasing values in the 100–115 ppbv range. From 1875 to 1957 CE, the record indicates a monotonic increase from 114±4 to 147±6 ppbv. The ice core multisite CO record exhibits an excellent overlap with the atmospheric CO record from Greenland firn air which spans the 1950–2010 CE time period. The combined ice core and firn air CO history, spanning 1700–2010 CE, provides useful constraints for future model studies of atmospheric changes since the preindustrial period. International audience

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    Climate of the Past (CP)
    Other literature type . 2021
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    https://doi.org/10.5194/cp-202...
    Preprint . 2021 . Peer-reviewed
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    Climate of the Past (CP)
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    Climate of the Past
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      https://doi.org/10.5194/cp-202...
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    Authors: Casal, J.; Gómez-Ramos, M.; Moro, A.M.; Corsi, A.;

    The Transfer to the Continuum method has been applied to describe the 11Li(p, pn) and 14Be(p, pn) reactions in inverse kinematics, using structure overlaps computed within a full three-body model for the projectile. Calculations agree with the available experimental data on the unbound 10Li and 13Be nuclei. Ministerio de Ciencia, Innovación y Universidades FIS2017-88410-P, FPA2016-77689-C2-1-R European Union's Horizon 2020 654002

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    arXiv.org e-Print Archive
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    Journal of Physics : Conference Series
    Other literature type . Article . 2020 . Peer-reviewed
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    Authors: Lorc��, C��dric;

    We review some of the recent developments regarding mass, angular momentum and pressure forces inside hadrons. These properties are all encoded in the energy-momentum tensor of the system, which is described at the non-perturbative level in terms of gravitational form factors. Similarly to electromagnetic form factors, Fourier transforms of gravitational form factors allow one to map out the distribution of the above mechanical properties in position space, providing a whole new way of studying in detail the internal structure of hadrons. 5 pages, 2 figures, contribution to the proceedings of the 27th International Nuclear Physics Conference (INPC) 2019, July 29- August 2, Glasgow, UK

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    Journal of Physics : Conference Series
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      Journal of Physics : Conference Series
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    Authors: Banks, William E.; Moncel, Marie-Helene; Raynal, J.P.; Cobos, MC; +7 Authors

    International audience; Abstract Middle Paleolithic Neanderthal populations occupied Eurasia for at least 250,000 years prior to the arrival of anatomically modern humans. While a considerable body of archaeological research has focused on Neanderthal material culture and subsistence strategies, little attention has been paid to the relationship between regionally specific cultural trajectories and their associated existing fundamental ecological niches, nor to how the latter varied across periods of climatic variability. We examine the Middle Paleolithic archaeological record of a naturally constrained region of Western Europe between 82,000 and 60,000 years ago using ecological niche modeling methods. Evaluations of ecological niche estimations, in both geographic and environmental dimensions, indicate that 70,000 years ago the range of suitable habitats exploited by these Neanderthal populations contracted and shifted. These ecological niche dynamics are the result of groups continuing to occupy habitual territories that were characterized by new environmental conditions during Marine Isotope Stage 4. The development of original cultural adaptations permitted this territorial stability.

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    Authors: Domingo-Pardo; C.; Babiano-Suarez; V.; +203 Authors

    The idea of slow-neutron capture nucleosynthesis formulated in 1957 triggered a tremendous experimental effort in different laboratories worldwide to measure the relevant nuclear physics input quantities, namely (n, γ) cross sections over the stellar temperature range (from few eV up to several hundred keV) for most of the isotopes involved from Fe up to Bi. A brief historical review focused on total energy detectors will be presented to illustrate how advances in instrumentation have led to the assessment of new aspects of s-process nucleosynthesis and to the progressive refinement of stellar models. A summary will be presented on current efforts to develop new detection concepts, such as the Total-Energy Detector with γ-ray imaging capability (i-TED). The latter is based on the simultaneous combination of Compton imaging with neutron time-of-flight (TOF) techniques, in order to achieve a superior level of sensitivity and selectivity in the measurement of stellar neutron capture rates. European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (ERC Consolidator Grant project HYMNS) 681740 Instituto de Salud Carlos III Spanish Government FPA2014-52823-C2-1-P FPA2017-83946-C2-1-P Consejo Superior de Investigaciones Cientificas (CSIC) PIE-201750I26 Program Severo Ochoa SEV-2014-0398

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    ROBIS
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    https://doi.org/10.48550/arxiv...
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    Authors: Thibaud Saos; Sophie Grégoire; Jean-Jacques Bahain; Thomas Higham; +11 Authors

    This paper presents new archaeological material and first dates on Upper Pleistocene layers at the site of La Crouzade cave (Gruissan, Aude, France). The site was first excavated by T. and P. Héléna at the beginning of the twentieth century, and the excavations were recently completed during three years (2016–2018) of systematic campaigns. We obtained dates from Middle Palaeolithic layers using two methods: AMS 14C dates were obtained from bone and charcoal, and combined ESR-U series dating was undertaken on horse teeth. Together, these methods allowed us to date this Mousterian sequence to 49,776–44805 cal BP for the deepest level (layer C8) and from 42,000 ± 3000 years BP for the top (layer C6). The Upper Palaeolithic layers are preserved only as patches in the actual excavation area, but a date was obtained from a piece of charcoal collected from a small hearth preserved in the first layer (C5) above Middle Palaeolithic deposits, which indicates an age similar to that of a modern human maxillary previously analysed and re-dated here from 36,014 to 34402 cal BP, confirming its stratigraphic attribution. The Middle Palaeolithic lithics at the site were first described as para-Charentian cultural facies following typological analyses. The revision of the earlier collection supplemented with the new material, using a technological approach, allow to identify two layers dominated by Levallois production followed by discoid production (Layers C8 and C6) surrounding an original assemblage (layer C7), characterised by a dominant Levallois production completed by three secondary production systems of equal importance, including discoid, SSDA and a Quina-like production. The faunal spectrum predominantly comprises an assemblage of Pleistocene large mammals, and biochronological studies corroborate the dates obtained.

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    Authors: D.-D. Rousseau; D.-D. Rousseau; P. Antoine; N. Boers; +11 Authors

    The global character of the millennial-scale climate variability associated with the Dansgaard-Oeschger (DO) events in Greenland has been well-established for the last glacial cycle. Mainly due to the sparsity of reliable data, however, the spatial coherence of corresponding variability during the penultimate cycle is less clear. New investigations of European loess records from Marine Isotope Stage (MIS) 6 reveal the occurrence of alternating loess intervals and paleosols (incipient soil horizons), similar to those from the last climatic cycle. These paleosols are correlated, based on their stratigraphical position and numbers as well as available optically stimulated luminescence (OSL) dates, with in-terstadials described in various Northern Hemisphere records and in GLt_syn, the synthetic 800 kyr record of Greenland ice core δ 18 O. Therefore, referring to the interstadials described in the record of the last climate cycle in European loess sequences, the four MIS 6 interstadials can confidently be interpreted as DO-like events of the penultimate climate cycle. Six more interstadials are identified from proxy measurements performed on the same interval, leading to a total of 10 interstadials with a DO-like event status. The statistical similarity between the millennial-scale loess-paleosol oscillations during the last and penultimate climate cycle provides direct empirical evidence that the cycles of the penultimate cycle are indeed of the same nature as the DO cycles originally discovered for the last glacial cycle. Our results thus imply that their underlying cause and global imprint were characteristic of at least the last two climate cycles. International audience (IF 4.29; Q1)

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