- home
- Advanced Search
- Digital Humanities and Cultural Heritage
- Publications
- Other research products
- National Health and Medical Researc...
- Wellcome Trust
- Digital Humanities and Cultural Heritage
- Publications
- Other research products
- National Health and Medical Researc...
- Wellcome Trust
Loading
description Publicationkeyboard_double_arrow_right Article 2019 Australia, Netherlands, Finland, Netherlands, Denmark, Belgium, Netherlands, Belgium, United KingdomPublisher:Elsevier BV Funded by:NIH | University of Washington ..., NIH | Methodologies to Enhance ..., WT | Global Atlas of Podoconio... +12 projectsNIH| University of Washington Center for Demography and Economics of Aging-Overall ,NIH| Methodologies to Enhance Understanding of HIV-Associated Social Determinants ,WT| Global Atlas of Podoconiosis ,NIH| Implementing mental health interventions for pregnant adolescents in primary care LMIC contexts ,NIH| Long term outcomes of therapy in women initiated on lifelong ART because of pregnancy in DR Congo ,NHMRC| Increasing knowledge about substance use, mental health and harms, and interventions to prevent and reduce harm ,FCT| Associated Laboratory for Green Chemistry - Clean Technologies and Processes ,NIH| Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South Africa ,MESTD| Functional, Functionalized and Advanced Nanomaterials ,NIH| Causal Pathways to population health impact of HIV antiretroviral treatment ,NIH| Central Africa IeDEA ,NIH| CARDIOMETABOLIC DISEASE & RISK FACTORS AMONG OLDER ADULTS IN SUB-SAHARAN AFRICA ,NIH| Training Tanzanian Researchers for HIV/AIDS Implementation Science ,NHMRC| Assessing the population health impact of illicit drug use: prevalence, trajectories, and contributions to disease burden ,NIH| New Methods for the design and evaluation of large HIV prevention interventionsFrank, Tahvi D; Carter, Austin; Jahagirdar, Deepa; Biehl, Molly H; Douwes-Schultz, Dirk; Larson, Samantha Leigh; Arora, Megha; Dwyer-Lindgren, Laura; Steuben, Krista M; Abbastabar, Hedayat; Abu-Raddad, Laith Jamal; Abyu, Direslgne Misker; Adabi, Maryam; Adebayo, Oladimeji M; Adekanmbi, Victor; Adetokunboh, Olatunji O; Ahmadi, Alireza; Ahmadi, Keivan; Ahmadian, Elham; Ahmadpour, Ehsan; Ahmed, Muktar Beshir; Akal, Chalachew Genet; Alahdab, Fares; Alam, Noore; Albertson, Samuel B; Alemnew, Birhan Tamene T; Alene, Kefyalew Addis; Alipour, Vahid; Alvis-Guzman, Nelson; Amini, Saeed; Anbari, Zohreh; Anber, Nahla Hamed; Anjomshoa, Mina; Antonio, Carl Abelardo T; Arabloo, Jalal; Aremu, Olatunde; Areri, Habtamu Abera; Asfaw, Ephrem Tsegay; Ashagre, Alebachew Fasil; Asmelash, Daniel; Asrat, Anemaw A; Avokpaho, Euripide FGA; Awasthi, Ashish; Awoke, Nefsu; Ayanore, Martin Amogre; Azari, Samad; Badawi, Alaa; Bagherzadeh, Mojtaba; Banach, Maciej; Barac, Aleksandra; Bärnighausen, Till Winfried; Basu, Sanjay; Bedi, Neeraj; Behzadifar, Masoud; Bekele, Bayu Begashaw; Belay, Saba Abraham; Belay, Yared Belete; Belayneh, Yaschilal Muche; Berhane, Adugnaw; Bhat, Anusha Ganapati; Bhattacharyya, Krittika; Biadgo, Belete; Bijani, Ali; Bin Sayeed, Muhammad Shahdaat; Bitew, Helen; Blinov, Andrew; Bogale, Kassawmar Angaw; Bojia, Hunduma Amensisa; Burugina Nagaraja, Sharath BN; Butt, Zahid A; Cahuana-Hurtado, Lucero; Campuzano Rincon, Julio Cesar; Carvalho, Félix; Chattu, Vijay Kumar; Christopher, Devasahayam J; Chu, Dinh-Toi; Crider, Raquel; Dahiru, Tukur; Dandona, Lalit; Dandona, Rakhi; Daryani, Ahmad; das Neves, José; De Neve, Jan-Walter; Degenhardt, Louisa; Demeke, Feleke Mekonnen; Demis, Asmamaw Bizuneh; Demissie, Dereje Bayissa; Demoz, Gebre Teklemariam; Deribe, Kebede; Des Jarlais, Don; Dhungana, Govinda Prasad; Diaz, Daniel; Djalalinia, Shirin; Do, Huyen Phuc; Doan, Linh Phuong; Duber, Herbert; Dubey, Manisha; Dubljanin, Eleonora; Duken, Eyasu Ejeta; Duko Adema, Bereket; Effiong, Andem; Eftekhari, Aziz; El Sayed Zaki, Maysaa; El-Jaafary, Shaimaa I; El-Khatib, Ziad; Elsharkawy, Aisha; Endries, Aman Yesuf; Eskandarieh, Sharareh; Eyawo, Oghenowede; Farzadfar, Farshad; Fatima, Batool; Fentahun, Netsanet; Fernandes, Eduarda; Filip, Irina; Fischer, Florian; Folayan, Morenike Oluwatoyin; Foroutan, Masoud; Fukumoto, Takeshi; Fullman, Nancy; Garcia-Basteiro, Alberto L; Gayesa, Reta Tsegaye; Gebremedhin, Ketema Bizuwork; Gebremeskel, Gebreamlak Gebremedhn Gebremedhn; Gebreyohannes, Kelali Kalaye; Gedefaw, Getnet Azeze; Gelaw, Belayneh K; Gesesew, Hailay Abrha; Geta, Birhanu; Gezae, Kebede Embaye; Ghadiri, Keyghobad; Ghashghaee, Ahmad; Ginindza, Themba TG; Gugnani, Harish Chander; Guimarães, Rafael Alves; Haile, Michael Tamene; Hailu, Gessessew Bugssa; Haj-Mirzaian, Arvin; Haj-Mirzaian, Arya; Hamidi, Samer; Handanagic, Senad; Handiso, Demelash Woldeyohannes; Hanfore, Lolemo Kelbiso; Hasanzadeh, Amir; Hassankhani, Hadi; Hassen, Hamid Yimam; Hay, Simon I; Henok, Andualem; Hoang, Chi Linh; Hosgood, H Dean; Hosseinzadeh, Mehdi; Hsairi, Mohamed; Ibitoye, Segun Emmanuel; Idrisov, Bulat; Ikuta, Kevin S; Ilesanmi, Olayinka Stephen; Irvani, Seyed Sina Naghibi; Iwu, Chinwe Juliana; Jacobsen, Kathryn H; James, Spencer L; Jenabi, Ensiyeh; Jha, Ravi Prakash; Jonas, Jost B; Jorjoran Shushtari, Zahra; Kabir, Ali; Kabir, Zubair; Kadel, Rajendra; Kasaeian, Amir; Kassa, Belete; Kassa, Getachew Mullu; Kassa, Tesfaye Dessale; Kayode, Gbenga A; Kebede, Mihiretu M; Kefale, Adane Teshome; Kengne, Andre Pascal; Khader, Yousef Saleh; Khafaie, Morteza Abdullatif; Khalid, Nauman; Khan, Ejaz Ahmad; Khan, Gulfaraz; Khan, Junaid; Khang, Young-Ho; Khatab, Khaled; Khazaei, Salman; Khoja, Abdullah T; Kiadaliri, Aliasghar A; Kim, Yun Jin; Kisa, Adnan; Kisa, Sezer; Kochhar, Sonali; Komaki, Hamidreza; Koul, Parvaiz A; Koyanagi, Ai; Kuate Defo, Barthelemy; Kumar, G Anil; Kumar, Manasi; Kuupiel, Desmond; Lal, Dharmesh Kumar; Lee, Jane Jean-Hee; Lenjebo, Tsegaye Lolaso; Leshargie, Cheru Tesema; Magdy Abd El Razek, Hassan; Mahasha, Phetole Walter; Majeed, Azeem; Manafi, Navid; Martins-Melo, Francisco Rogerlândio; Meles, Gebrekiros Gebremichael; Meles, Hagazi Gebre; Meretoja, Tuomo J; Miller, Ted R; Moazen, Babak; Mohammad, Karzan Abdulmuhsin; Mohammed, Shafiu; Mohebi, Farnam; Mokdad, Ali H; Moodley, Yoshan; Moradi, Ghobad; Mossie, Tilahun Belete; Mousavi, Seyyed Meysam; Muthupandian, Saravanan; Nazari, Javad; Ndwandwe, Duduzile Edith; Ningrum, Dina Nur Anggraini; Nnaji, Chukwudi A; Noubiap, Jean Jacques; Nourollahpour Shiadeh, Malihe; Obsa, Mohammed Suleiman; Olagunju, Andrew T; Olagunju, Tinuke O; Olum, Solomon; Padubidri, Jagadish Rao; Pakhale, Smita; Pakpour, Amir H; Paulos, Kebreab; Pepito, Veincent Christian Filipino; Pourshams, Akram; Rabiee, Mohammad; Rabiee, Navid; Rafiei, Alireza; Rahim, Fakher; Rahimi-Movaghar, Vafa; Renjith, Vishnu; Reta, Melese Abate; Rezai, Mohammad Sadegh; Rostami, Ali; Saeedi Moghaddam, Sahar; Safari, Saeed; Sagar, Rajesh; Salomon, Joshua A; Samy, Abdallah M; Schutte, Aletta Elisabeth; Shabaninejad, Hosein; Shamsizadeh, Morteza; Sharifi, Hamid; Shibuya, Kenji; Silva, Diego Augusto Santos; Sisay, Mekonnen; Sokhan, Anton; Soshnikov, Sergey; Stein, Dan J; Sufiyan, Mu'awiyyah Babale; Sunguya, Bruno F; Tadesse, Birkneh Tilahun; Tadesse, Degena Bahrey; Taveira, Nuno; Tesfay, Fisaha Haile; Thapa, Subash; Topp, Stephanie M; Tran, Bach Xuan; Tran, Khanh Bao; Ullah, Irfan; Unnikrishnan, Bhaskaran; Uthman, Olalekan A; Waheed, Yasir; Wijeratne, Tissa; Wolde, Haileab Fekadu; Wonde, Tewodros Eshete; Yotebieng, Marcel; Zaidi, Zoubida; Ziapour, Arash;pmc: PMC6934077
handle: 11541.2/33253 , 10067/1651020151162165141 , 10138/310381 , 1854/LU-8626802
Background Understanding the patterns of HIV/AIDS epidemics is crucial to tracking and monitoring the progress of prevention and control efforts in countries. We provide a comprehensive assessment of the levels and trends of HIV/AIDS incidence, prevalence, mortality, and coverage of antiretroviral therapy (ART) for 1980-2017 and forecast these estimates to 2030 for 195 countries and territories. Methods We determined a modelling strategy for each country on the basis of the availability and quality of data. For countries and territories with data from population-based seroprevalence surveys or antenatal care clinics, we estimated prevalence and incidence using an open-source version of the Estimation and Projection Package-a natural history model originally developed by the UNAIDS Reference Group on Estimates, Modelling, and Projections. For countries with cause-specific vital registration data, we corrected data for garbage coding (ie, deaths coded to an intermediate, immediate, or poorly defined cause) and HIV misclassification. We developed a process of cohort incidence bias adjustment to use information on survival and deaths recorded in vital registration to back-calculate HIV incidence. For countries without any representative data on HIV, we produced incidence estimates by pulling information from observed bias in the geographical region. We used a re-coded version of the Spectrum model (a cohort component model that uses rates of disease progression and HIV mortality on and off ART) to produce age-sex-specific incidence, prevalence, and mortality, and treatment coverage results for all countries, and forecast these measures to 2030 using Spectrum with inputs that were extended on the basis of past trends in treatment scale-up and new infections. Findings Global HIV mortality peaked in 2006 with 1.95 million deaths (95% uncertainty interval 1.87-2.04) and has since decreased to 0.95 million deaths (0.91-1.01) in 2017. New cases of HIV globally peaked in 1999 (3.16 million, 2.79-3.67) and since then have gradually decreased to 1.94 million (1.63-2.29) in 2017. These trends, along with ART scale-up, have globally resulted in increased prevalence, with 36.8 million (34.8-39.2) people living with HIV in 2017. Prevalence of HIV was highest in southern sub-Saharan Africa in 2017, and countries in the region had ART coverage ranging from 65.7% in Lesotho to 85.7% in eSwatini. Our forecasts showed that 54 countries will meet the UNAIDS target of 81% ART coverage by 2020 and 12 countries are on track to meet 90% ART coverage by 2030. Forecasted results estimate that few countries will meet the UNAIDS 2020 and 2030 mortality and incidence targets. Interpretation Despite progress in reducing HIV-related mortality over the past decade, slow decreases in incidence, combined with the current context of stagnated funding for related interventions, mean that many countries are not on track to reach the 2020 and 2030 global targets for reduction in incidence and mortality. With a growing population of people living with HIV, it will continue to be a major threat to public health for years to come. The pace of progress needs to be hastened by continuing to expand access to ART and increasing investments in proven HIV prevention initiatives that can be scaled up to have population-level impact. Copyright (C) 2019 The Author(s). Published by Elsevier Ltd. Peer reviewed
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6934077Data sources: PubMed CentralFachrepositorium LebenswissenschaftenArticle . 2019License: CC BYData sources: Fachrepositorium Lebenswissenschaftenhttps://hdl.handle.net/10067/1...Article . 2019Data sources: Institutional Repository Universiteit AntwerpenUniversity of Southern Denmark Research OutputArticle . 2019Data sources: University of Southern Denmark Research OutputSpiral - Imperial College Digital RepositoryArticle . 2019Data sources: Spiral - Imperial College Digital RepositoryUniversity of Lincoln Institutional RepositoryArticle . 2019 . Peer-reviewedData sources: University of Lincoln Institutional RepositoryGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyHELDA - Digital Repository of the University of HelsinkiArticle . 2019 . Peer-reviewedData sources: HELDA - Digital Repository of the University of HelsinkiGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyUniSA Research Outputs RepositoryArticle . 2019 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/s2352-3018(19)30196-1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 271 citations 271 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!visibility 35visibility views 35 download downloads 105 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6934077Data sources: PubMed CentralFachrepositorium LebenswissenschaftenArticle . 2019License: CC BYData sources: Fachrepositorium Lebenswissenschaftenhttps://hdl.handle.net/10067/1...Article . 2019Data sources: Institutional Repository Universiteit AntwerpenUniversity of Southern Denmark Research OutputArticle . 2019Data sources: University of Southern Denmark Research OutputSpiral - Imperial College Digital RepositoryArticle . 2019Data sources: Spiral - Imperial College Digital RepositoryUniversity of Lincoln Institutional RepositoryArticle . 2019 . Peer-reviewedData sources: University of Lincoln Institutional RepositoryGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyHELDA - Digital Repository of the University of HelsinkiArticle . 2019 . Peer-reviewedData sources: HELDA - Digital Repository of the University of HelsinkiGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyUniSA Research Outputs RepositoryArticle . 2019 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/s2352-3018(19)30196-1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2018 United KingdomPublisher:Springer Science and Business Media LLC Funded by:WT, NHMRC | Focus on the uterus: basi...WT ,NHMRC| Focus on the uterus: basic and translational research strategies to address key issues in women’s health. Fertility, infertility, endometrial and pregnancy disorders.Authors: Mike Clarke;Mike Clarke;Abstract Six years after the launch of Systematic Reviews by Biomed Central, this article is part of the celebration of the journal. It contains personal reflections on the past, present and future of systematic reviews, using examples relevant to the role of systematic reviews in cataloguing and analysing research, assessing quality and planning new studies. The focus is on the most common of the various types of systematic review in health and social care, namely those assessing the effects of interventions.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6204283Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s13643-018-0833-3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 11 citations 11 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6204283Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s13643-018-0833-3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 United Kingdom, SpainPublisher:Frontiers Media SA Funded by:NHMRC | Uncoupled Research Fellow..., UKRI | Linking electronic health..., WT +4 projectsNHMRC| Uncoupled Research Fellowship ,UKRI| Linking electronic health records with passive smartphone activity data to predict outcomes in psychotic disorders ,WT ,UKRI| What are the clinical and educational risk factors for poor academic outcomes in children with Autistic Spectrum Disorder? ,UKRI| The Alan Turing Institute ,EC| INCA ,UKRI| "Information about Drinking for Ex-serving personnel (InDEx)" - Development of a personalised alcohol appAuthors: Sumithra Velupillai; Sumithra Velupillai; Sumithra Velupillai; Gergö Hadlaczky; +21 AuthorsSumithra Velupillai; Sumithra Velupillai; Sumithra Velupillai; Gergö Hadlaczky; Gergö Hadlaczky; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Genevieve M. Gorrell; Nomi Werbeloff; Dong Nguyen; Dong Nguyen; Rashmi Patel; Rashmi Patel; Daniel Leightley; Johnny Downs; Johnny Downs; Matthew Hotopf; Matthew Hotopf; Rina Dutta; Rina Dutta;pmc: PMC6381841
pmid: 30814958
This manuscript was written as a result of a workshop that was held at the Institute of Psychiatry, Psychology and Neuroscience, King’s College London, financially supported by the European Science Foundation (ESF) Research Networking Programme Evaluating Information Access Systems: http://elias-network.eu/. SV is supported by the Swedish Research Council (2015-00359) and the Marie Skłodowska Curie Actions, Cofund, Project INCA 600398. EB-G is partially supported by grants from Instituto de Salud Carlos III (ISCIII PI13/02200; PI16/01852), Delegación del Gobierno para el Plan Nacional de Drogas (20151073); American Foundation for Suicide Prevention (AFSP) (LSRG- 1-005-16). NW is supported by the UCLH NIHR Biomedical Research Centre. DN is supported by The Alan Turing Institute under the EPSRC grant EP/N510129/1, with an Alan Turing Institute Fellowship (TU/A/000006). RP has received support from a Medical Research Council (MRC) Health Data Research UK Fellowship (MR/S003118/1) and a Starter Grant for Clinical Lecturers (SGL015/1020) supported by the Academy of Medical Sciences, The Wellcome Trust, MRC, British Heart Foundation, Arthritis Research UK, the Royal College of Physicians and Diabetes UK. DL is supported by the UK Medical Research Council under grant MR/N028244/2 and the King’s Centre for Military Health Research. JD is supported by a Medical Research Council (MRC) Clinical Research Training Fellowship (MR/L017105/1). RD is funded by a Clinician Scientist Fellowship (research project e-HOST-IT) from the Health Foundation in partnership with the Academy of Medical Sciences Risk assessment of suicidal behavior is a time-consuming but notoriously inaccurate activity formental health services globally. In the last 50 years a large number of tools have been designed for suicide risk assessment, and tested in a wide variety of populations, but studies show that these tools suffer fromlow positive predictive values.More recently, advances in research fields such as machine learning and natural language processing applied on large datasets have shown promising results for health care, and may enable an important shift in advancing precision medicine. In this conceptual review, we discuss established risk assessment tools and examples of novel data-driven approaches that have been used for identification of suicidal behavior and risk. We provide a perspective on the strengths and weaknesses of these applications to mental health-related data, and suggest research directions to enable improvement in clinical practice
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6381841Data sources: PubMed CentralRecolector de Ciencia Abierta, RECOLECTAArticle . 2019Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3389/fpsyt.2019.00036&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 46 citations 46 popularity Top 1% influence Top 10% impulse Top 10% Powered by BIP!visibility 5visibility views 5 download downloads 100 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6381841Data sources: PubMed CentralRecolector de Ciencia Abierta, RECOLECTAArticle . 2019Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3389/fpsyt.2019.00036&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2020 Turkey, Turkey, France, Netherlands, United Kingdom, TurkeyPublisher:American Society of Hematology Funded by:NHMRC | Delineating aberrant adap..., EC | iDysChart, FWF | Novel immunodeficiency un... +1 projectsNHMRC| Delineating aberrant adaptive immune responses due to germline mutations in the PI3K signalling pathway ,EC| iDysChart ,FWF| Novel immunodeficiency unravels immune homeostasis mechanism ,WT| The immunopathogenesis of Epstein-Barr virus-associated malignancies.Sujal Ghosh; Sevgi Köstel Bal; Emily S.J. Edwards; Bethany Pillay; Raúl Jiménez Heredia; Funda Erol Cipe; Geetha Rao; Elisabeth Salzer; Samaneh Zoghi; Hassan Abolhassani; Tooba Momen; Emma Gostick; David Price; Yu Zhang; Andrew J. Oler; Claudia Gonzaga-Jauregui; Baran Erman; Ayse Metin; Inci Ilhan; Sule Haskologlu; Candan Islamoglu; Kubra Baskin; Serdar Ceylaner; Ebru Yilmaz; Ekrem Unal; Musa Karakukcu; Dagmar Berghuis; Theresa Cole; Aditya Gupta; Fabian Hauck; Hubert Kogler; Andy I. M. Hoepelman; Safa Baris; Elif Karakoc-Aydiner; Ahmet Ozen; Leo Kager; Dirk Holzinger; Michael Paulussen; Renate Krüger; Roland Meisel; Prasad T. Oommen; Emma C. Morris; Bénédicte Neven; Austen Worth; Joris M. van Montfrans; Pieter L. A. Fraaij; Sharon Choo; Figen Dogu; E. Graham Davies; Siobhan O. Burns; Gregor Dückers; Ruy Perez Becker; Horst von Bernuth; Sylvain Latour; Maura Faraci; Marco Gattorno; Helen C. Su; Qiang Pan-Hammarström; Lennart Hammarström; Michael J. Lenardo; Cindy S. Ma; Tim Niehues; Asghar Aghamohammadi; Nima Rezaei; Aydan Ikinciogullari; Stuart G. Tangye; Arjan C. Lankester; Kaan Boztug; Ebmt;pmc: PMC7735164
handle: 1887/3184827 , 11424/243206
Abstract Biallelic mutations in the genes encoding CD27 or its ligand CD70 underlie inborn errors of immunity (IEIs) characterized predominantly by Epstein-Barr virus (EBV)-associated immune dysregulation, such as chronic viremia, severe infectious mononucleosis, hemophagocytic lymphohistiocytosis (HLH), lymphoproliferation, and malignancy. A comprehensive understanding of the natural history, immune characteristics, and transplant outcomes has remained elusive. Here, in a multi-institutional global collaboration, we collected the clinical information of 49 patients from 29 families (CD27, n = 33; CD70, n = 16), including 24 previously unreported individuals and identified a total of 16 distinct mutations in CD27, and 8 in CD70, respectively. The majority of patients (90%) were EBV+ at diagnosis, but only ∼30% presented with infectious mononucleosis. Lymphoproliferation and lymphoma were the main clinical manifestations (70% and 43%, respectively), and 9 of the CD27-deficient patients developed HLH. Twenty-one patients (43%) developed autoinflammatory features including uveitis, arthritis, and periodic fever. Detailed immunological characterization revealed aberrant generation of memory B and T cells, including a paucity of EBV-specific T cells, and impaired effector function of CD8+ T cells, thereby providing mechanistic insight into cellular defects underpinning the clinical features of disrupted CD27/CD70 signaling. Nineteen patients underwent allogeneic hematopoietic stem cell transplantation (HSCT) prior to adulthood predominantly because of lymphoma, with 95% survival without disease recurrence. Our data highlight the marked predisposition to lymphoma of both CD27- and CD70-deficient patients. The excellent outcome after HSCT supports the timely implementation of this treatment modality particularly in patients presenting with malignant transformation to lymphoma.
NARCIS arrow_drop_down NARCIS; BloodOther literature type . Article . 2020 . Peer-reviewedİstinye University Institutional RepositoryArticle . 2020Data sources: İstinye University Institutional RepositoryMarmara University Open Access SystemArticle . 2020Data sources: Marmara University Open Access SystemUniversitätsbibliographie, Universität Duisburg-EssenArticle . 2020Data sources: Universitätsbibliographie, Universität Duisburg-EssenNARCIS; BloodArticle . 2020Mémoires en Sciences de l'Information et de la CommunicationArticle . 2020Full-Text: https://hal.science/hal-03066024/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1182/blood.2020007763&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 66 citations 66 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert NARCIS arrow_drop_down NARCIS; BloodOther literature type . Article . 2020 . Peer-reviewedİstinye University Institutional RepositoryArticle . 2020Data sources: İstinye University Institutional RepositoryMarmara University Open Access SystemArticle . 2020Data sources: Marmara University Open Access SystemUniversitätsbibliographie, Universität Duisburg-EssenArticle . 2020Data sources: Universitätsbibliographie, Universität Duisburg-EssenNARCIS; BloodArticle . 2020Mémoires en Sciences de l'Information et de la CommunicationArticle . 2020Full-Text: https://hal.science/hal-03066024/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1182/blood.2020007763&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2020 Finland, Italy, ItalyPublisher:Springer Science and Business Media LLC Funded by:NIH | VITAMIN INTERVENTION FOR ..., NIH | Genetics of ischemic stro..., WT | Understanding the genetic... +19 projectsNIH| VITAMIN INTERVENTION FOR STROKE PREVENTION ,NIH| Genetics of ischemic stroke in the SiGN Consortium ,WT| Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics. ,NHMRC| Australian Stroke Genetics Collaborative - Genome-wide association study in ischaemic stroke ,NIH| THE BALTIMORE LONGITUDINAL STUDY OF HUMAN AGING ,NIH| ISGS: The Ischemic Stroke Genetics Study ,NIH| MULTICENTERED STUDY OF STROKE GENETICS ,NIH| Genetic Risk to Stroke in Smokers and Nonsmokers in Two Ethnic Groups ,NIH| Genetics Of Stroke ,EC| GEUVADIS ,NIH| Data Mgmt &Analysis Core - The NINDS International Stroke Genetics Consortium St ,WT| A genome wide association study in ischaemic stroke. ,NIH| GWAS of Hormone Treatment and CVD and Metabolic Outcomes in the WHI ,NIH| A Center for GEI Association Studies ,NIH| Genetics of Early Onset-Stroke ,NIH| Genome Wide Association Coordinating Center ,NIH| Genetics of Early-Onset Ischemic Stroke Consortium ,NIH| Research Training in the Epidemiology of Aging ,WT| WTCCC2 core activities ,NIH| CORE--ADIPOSE TISSUE BIOLOGY AND BASIC MECHANISMS ,NIH| Randomized Clinical Trials - Whole Genome Studies Coordinating Center ,NIH| A Genome-wide Association Study for Early-Onset Myocardial InfarctionAuthors: Stefano Mammola; Diego Fontaneto; Alejandro Martínez; Filipe Chichorro;Stefano Mammola; Diego Fontaneto; Alejandro Martínez; Filipe Chichorro;handle: 10138/326141
Many believe that the quality of a scientific publication is as good as the science it cites. However, quantifications of how features of reference lists affect citations remain sparse. We examined seven numerical characteristics of reference lists of 50,878 research articles published in 17 ecological journals between 1997 and 2017. Over this period, significant changes occurred in reference lists' features. On average, more recent papers have longer reference lists and cite more high Impact Factor papers and fewer non-journal publications. We also show that highly cited articles across the ecological literature have longer reference lists, cite more recent and impactful references, and include more self-citations. Conversely, the proportion of 'classic' papers and non-journal publications cited, as well as the temporal span of the reference list, have no significant influence on articles' citations. From this analysis, we distill a recipe for crafting impactful reference lists, at least in ecology. Peer reviewed
CNR ExploRA arrow_drop_down HELDA - Digital Repository of the University of HelsinkiArticle . 2021 . Peer-reviewedData sources: HELDA - Digital Repository of the University of Helsinkiadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11192-020-03759-0&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routeshybrid 28 citations 28 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert CNR ExploRA arrow_drop_down HELDA - Digital Repository of the University of HelsinkiArticle . 2021 . Peer-reviewedData sources: HELDA - Digital Repository of the University of Helsinkiadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11192-020-03759-0&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2015Publisher:Elsevier BV Funded by:WT | Thai health-risk transist..., NHMRC | Thai Health-Risk Transiti..., NHMRC | Thai health-risk transiti...WT| Thai health-risk transistion: Anational cohort study. ,NHMRC| Thai Health-Risk Transition: a National Cohort Study - Phase II ,NHMRC| Thai health-risk transition: a national cohort studyWimalin Rimpeekool; Sam-ang Seubsman; Cathy Banwell; Martyn D. Kirk; Vasoontara Yiengprugsawan; Adrian Sleigh;This paper reviews the evolution of Thai food and nutrition label policies and Thailand’s international role relating to food product safety and standards. The historical record has been interpreted to identify future trends and challenges related to food labelling. These challenges are arising in Thailand and many similar emerging economies. Thailand has a good reputation in world food markets and is now becoming a global leader in food production and export. It has become deeply involved with regulations and standards applied by World Trade Organization and Codex Alimentarius while serving its own population with a safe and secure food supply. For consumers considering Thai food products, food labels can provide useful nutrition information and help build trust. Thais began a century ago with policies and laws to enhance food safety and to protect Thai consumers. During the lengthy journey from national to global standards Thai food labels have evolved and now contribute to international food labelling policies. This contribution comes from the perspective of a leading middle income south-east Asian food producer now trading with high income countries around the world. The story of that journey – a case study for many other countries in a similar situation – has not previously been told. This article provides information for policy makers dealing with food labelling, embedding trends and tensions for one middle income food exporter in a long history. Information captured here should be helpful for other middle income countries, especially those with limited records. This strategic knowledge will enable better decisions for future policies. Highlights • Thai food labels show transition from closed agriculture to global agribusiness • Thai food quality follows investment in food science and technology after WW2 • Thai food labels address transition from hunger to plenty and international rules • It is difficult to harmonize nutrition labels among the countries of SE Asia • Domestic protection versus global food trade creates tension and new rules
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4608433Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.foodpol.2015.07.011&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 28 citations 28 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4608433Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.foodpol.2015.07.011&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu
Loading
description Publicationkeyboard_double_arrow_right Article 2019 Australia, Netherlands, Finland, Netherlands, Denmark, Belgium, Netherlands, Belgium, United KingdomPublisher:Elsevier BV Funded by:NIH | University of Washington ..., NIH | Methodologies to Enhance ..., WT | Global Atlas of Podoconio... +12 projectsNIH| University of Washington Center for Demography and Economics of Aging-Overall ,NIH| Methodologies to Enhance Understanding of HIV-Associated Social Determinants ,WT| Global Atlas of Podoconiosis ,NIH| Implementing mental health interventions for pregnant adolescents in primary care LMIC contexts ,NIH| Long term outcomes of therapy in women initiated on lifelong ART because of pregnancy in DR Congo ,NHMRC| Increasing knowledge about substance use, mental health and harms, and interventions to prevent and reduce harm ,FCT| Associated Laboratory for Green Chemistry - Clean Technologies and Processes ,NIH| Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South Africa ,MESTD| Functional, Functionalized and Advanced Nanomaterials ,NIH| Causal Pathways to population health impact of HIV antiretroviral treatment ,NIH| Central Africa IeDEA ,NIH| CARDIOMETABOLIC DISEASE & RISK FACTORS AMONG OLDER ADULTS IN SUB-SAHARAN AFRICA ,NIH| Training Tanzanian Researchers for HIV/AIDS Implementation Science ,NHMRC| Assessing the population health impact of illicit drug use: prevalence, trajectories, and contributions to disease burden ,NIH| New Methods for the design and evaluation of large HIV prevention interventionsFrank, Tahvi D; Carter, Austin; Jahagirdar, Deepa; Biehl, Molly H; Douwes-Schultz, Dirk; Larson, Samantha Leigh; Arora, Megha; Dwyer-Lindgren, Laura; Steuben, Krista M; Abbastabar, Hedayat; Abu-Raddad, Laith Jamal; Abyu, Direslgne Misker; Adabi, Maryam; Adebayo, Oladimeji M; Adekanmbi, Victor; Adetokunboh, Olatunji O; Ahmadi, Alireza; Ahmadi, Keivan; Ahmadian, Elham; Ahmadpour, Ehsan; Ahmed, Muktar Beshir; Akal, Chalachew Genet; Alahdab, Fares; Alam, Noore; Albertson, Samuel B; Alemnew, Birhan Tamene T; Alene, Kefyalew Addis; Alipour, Vahid; Alvis-Guzman, Nelson; Amini, Saeed; Anbari, Zohreh; Anber, Nahla Hamed; Anjomshoa, Mina; Antonio, Carl Abelardo T; Arabloo, Jalal; Aremu, Olatunde; Areri, Habtamu Abera; Asfaw, Ephrem Tsegay; Ashagre, Alebachew Fasil; Asmelash, Daniel; Asrat, Anemaw A; Avokpaho, Euripide FGA; Awasthi, Ashish; Awoke, Nefsu; Ayanore, Martin Amogre; Azari, Samad; Badawi, Alaa; Bagherzadeh, Mojtaba; Banach, Maciej; Barac, Aleksandra; Bärnighausen, Till Winfried; Basu, Sanjay; Bedi, Neeraj; Behzadifar, Masoud; Bekele, Bayu Begashaw; Belay, Saba Abraham; Belay, Yared Belete; Belayneh, Yaschilal Muche; Berhane, Adugnaw; Bhat, Anusha Ganapati; Bhattacharyya, Krittika; Biadgo, Belete; Bijani, Ali; Bin Sayeed, Muhammad Shahdaat; Bitew, Helen; Blinov, Andrew; Bogale, Kassawmar Angaw; Bojia, Hunduma Amensisa; Burugina Nagaraja, Sharath BN; Butt, Zahid A; Cahuana-Hurtado, Lucero; Campuzano Rincon, Julio Cesar; Carvalho, Félix; Chattu, Vijay Kumar; Christopher, Devasahayam J; Chu, Dinh-Toi; Crider, Raquel; Dahiru, Tukur; Dandona, Lalit; Dandona, Rakhi; Daryani, Ahmad; das Neves, José; De Neve, Jan-Walter; Degenhardt, Louisa; Demeke, Feleke Mekonnen; Demis, Asmamaw Bizuneh; Demissie, Dereje Bayissa; Demoz, Gebre Teklemariam; Deribe, Kebede; Des Jarlais, Don; Dhungana, Govinda Prasad; Diaz, Daniel; Djalalinia, Shirin; Do, Huyen Phuc; Doan, Linh Phuong; Duber, Herbert; Dubey, Manisha; Dubljanin, Eleonora; Duken, Eyasu Ejeta; Duko Adema, Bereket; Effiong, Andem; Eftekhari, Aziz; El Sayed Zaki, Maysaa; El-Jaafary, Shaimaa I; El-Khatib, Ziad; Elsharkawy, Aisha; Endries, Aman Yesuf; Eskandarieh, Sharareh; Eyawo, Oghenowede; Farzadfar, Farshad; Fatima, Batool; Fentahun, Netsanet; Fernandes, Eduarda; Filip, Irina; Fischer, Florian; Folayan, Morenike Oluwatoyin; Foroutan, Masoud; Fukumoto, Takeshi; Fullman, Nancy; Garcia-Basteiro, Alberto L; Gayesa, Reta Tsegaye; Gebremedhin, Ketema Bizuwork; Gebremeskel, Gebreamlak Gebremedhn Gebremedhn; Gebreyohannes, Kelali Kalaye; Gedefaw, Getnet Azeze; Gelaw, Belayneh K; Gesesew, Hailay Abrha; Geta, Birhanu; Gezae, Kebede Embaye; Ghadiri, Keyghobad; Ghashghaee, Ahmad; Ginindza, Themba TG; Gugnani, Harish Chander; Guimarães, Rafael Alves; Haile, Michael Tamene; Hailu, Gessessew Bugssa; Haj-Mirzaian, Arvin; Haj-Mirzaian, Arya; Hamidi, Samer; Handanagic, Senad; Handiso, Demelash Woldeyohannes; Hanfore, Lolemo Kelbiso; Hasanzadeh, Amir; Hassankhani, Hadi; Hassen, Hamid Yimam; Hay, Simon I; Henok, Andualem; Hoang, Chi Linh; Hosgood, H Dean; Hosseinzadeh, Mehdi; Hsairi, Mohamed; Ibitoye, Segun Emmanuel; Idrisov, Bulat; Ikuta, Kevin S; Ilesanmi, Olayinka Stephen; Irvani, Seyed Sina Naghibi; Iwu, Chinwe Juliana; Jacobsen, Kathryn H; James, Spencer L; Jenabi, Ensiyeh; Jha, Ravi Prakash; Jonas, Jost B; Jorjoran Shushtari, Zahra; Kabir, Ali; Kabir, Zubair; Kadel, Rajendra; Kasaeian, Amir; Kassa, Belete; Kassa, Getachew Mullu; Kassa, Tesfaye Dessale; Kayode, Gbenga A; Kebede, Mihiretu M; Kefale, Adane Teshome; Kengne, Andre Pascal; Khader, Yousef Saleh; Khafaie, Morteza Abdullatif; Khalid, Nauman; Khan, Ejaz Ahmad; Khan, Gulfaraz; Khan, Junaid; Khang, Young-Ho; Khatab, Khaled; Khazaei, Salman; Khoja, Abdullah T; Kiadaliri, Aliasghar A; Kim, Yun Jin; Kisa, Adnan; Kisa, Sezer; Kochhar, Sonali; Komaki, Hamidreza; Koul, Parvaiz A; Koyanagi, Ai; Kuate Defo, Barthelemy; Kumar, G Anil; Kumar, Manasi; Kuupiel, Desmond; Lal, Dharmesh Kumar; Lee, Jane Jean-Hee; Lenjebo, Tsegaye Lolaso; Leshargie, Cheru Tesema; Magdy Abd El Razek, Hassan; Mahasha, Phetole Walter; Majeed, Azeem; Manafi, Navid; Martins-Melo, Francisco Rogerlândio; Meles, Gebrekiros Gebremichael; Meles, Hagazi Gebre; Meretoja, Tuomo J; Miller, Ted R; Moazen, Babak; Mohammad, Karzan Abdulmuhsin; Mohammed, Shafiu; Mohebi, Farnam; Mokdad, Ali H; Moodley, Yoshan; Moradi, Ghobad; Mossie, Tilahun Belete; Mousavi, Seyyed Meysam; Muthupandian, Saravanan; Nazari, Javad; Ndwandwe, Duduzile Edith; Ningrum, Dina Nur Anggraini; Nnaji, Chukwudi A; Noubiap, Jean Jacques; Nourollahpour Shiadeh, Malihe; Obsa, Mohammed Suleiman; Olagunju, Andrew T; Olagunju, Tinuke O; Olum, Solomon; Padubidri, Jagadish Rao; Pakhale, Smita; Pakpour, Amir H; Paulos, Kebreab; Pepito, Veincent Christian Filipino; Pourshams, Akram; Rabiee, Mohammad; Rabiee, Navid; Rafiei, Alireza; Rahim, Fakher; Rahimi-Movaghar, Vafa; Renjith, Vishnu; Reta, Melese Abate; Rezai, Mohammad Sadegh; Rostami, Ali; Saeedi Moghaddam, Sahar; Safari, Saeed; Sagar, Rajesh; Salomon, Joshua A; Samy, Abdallah M; Schutte, Aletta Elisabeth; Shabaninejad, Hosein; Shamsizadeh, Morteza; Sharifi, Hamid; Shibuya, Kenji; Silva, Diego Augusto Santos; Sisay, Mekonnen; Sokhan, Anton; Soshnikov, Sergey; Stein, Dan J; Sufiyan, Mu'awiyyah Babale; Sunguya, Bruno F; Tadesse, Birkneh Tilahun; Tadesse, Degena Bahrey; Taveira, Nuno; Tesfay, Fisaha Haile; Thapa, Subash; Topp, Stephanie M; Tran, Bach Xuan; Tran, Khanh Bao; Ullah, Irfan; Unnikrishnan, Bhaskaran; Uthman, Olalekan A; Waheed, Yasir; Wijeratne, Tissa; Wolde, Haileab Fekadu; Wonde, Tewodros Eshete; Yotebieng, Marcel; Zaidi, Zoubida; Ziapour, Arash;pmc: PMC6934077
handle: 11541.2/33253 , 10067/1651020151162165141 , 10138/310381 , 1854/LU-8626802
Background Understanding the patterns of HIV/AIDS epidemics is crucial to tracking and monitoring the progress of prevention and control efforts in countries. We provide a comprehensive assessment of the levels and trends of HIV/AIDS incidence, prevalence, mortality, and coverage of antiretroviral therapy (ART) for 1980-2017 and forecast these estimates to 2030 for 195 countries and territories. Methods We determined a modelling strategy for each country on the basis of the availability and quality of data. For countries and territories with data from population-based seroprevalence surveys or antenatal care clinics, we estimated prevalence and incidence using an open-source version of the Estimation and Projection Package-a natural history model originally developed by the UNAIDS Reference Group on Estimates, Modelling, and Projections. For countries with cause-specific vital registration data, we corrected data for garbage coding (ie, deaths coded to an intermediate, immediate, or poorly defined cause) and HIV misclassification. We developed a process of cohort incidence bias adjustment to use information on survival and deaths recorded in vital registration to back-calculate HIV incidence. For countries without any representative data on HIV, we produced incidence estimates by pulling information from observed bias in the geographical region. We used a re-coded version of the Spectrum model (a cohort component model that uses rates of disease progression and HIV mortality on and off ART) to produce age-sex-specific incidence, prevalence, and mortality, and treatment coverage results for all countries, and forecast these measures to 2030 using Spectrum with inputs that were extended on the basis of past trends in treatment scale-up and new infections. Findings Global HIV mortality peaked in 2006 with 1.95 million deaths (95% uncertainty interval 1.87-2.04) and has since decreased to 0.95 million deaths (0.91-1.01) in 2017. New cases of HIV globally peaked in 1999 (3.16 million, 2.79-3.67) and since then have gradually decreased to 1.94 million (1.63-2.29) in 2017. These trends, along with ART scale-up, have globally resulted in increased prevalence, with 36.8 million (34.8-39.2) people living with HIV in 2017. Prevalence of HIV was highest in southern sub-Saharan Africa in 2017, and countries in the region had ART coverage ranging from 65.7% in Lesotho to 85.7% in eSwatini. Our forecasts showed that 54 countries will meet the UNAIDS target of 81% ART coverage by 2020 and 12 countries are on track to meet 90% ART coverage by 2030. Forecasted results estimate that few countries will meet the UNAIDS 2020 and 2030 mortality and incidence targets. Interpretation Despite progress in reducing HIV-related mortality over the past decade, slow decreases in incidence, combined with the current context of stagnated funding for related interventions, mean that many countries are not on track to reach the 2020 and 2030 global targets for reduction in incidence and mortality. With a growing population of people living with HIV, it will continue to be a major threat to public health for years to come. The pace of progress needs to be hastened by continuing to expand access to ART and increasing investments in proven HIV prevention initiatives that can be scaled up to have population-level impact. Copyright (C) 2019 The Author(s). Published by Elsevier Ltd. Peer reviewed
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6934077Data sources: PubMed CentralFachrepositorium LebenswissenschaftenArticle . 2019License: CC BYData sources: Fachrepositorium Lebenswissenschaftenhttps://hdl.handle.net/10067/1...Article . 2019Data sources: Institutional Repository Universiteit AntwerpenUniversity of Southern Denmark Research OutputArticle . 2019Data sources: University of Southern Denmark Research OutputSpiral - Imperial College Digital RepositoryArticle . 2019Data sources: Spiral - Imperial College Digital RepositoryUniversity of Lincoln Institutional RepositoryArticle . 2019 . Peer-reviewedData sources: University of Lincoln Institutional RepositoryGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyHELDA - Digital Repository of the University of HelsinkiArticle . 2019 . Peer-reviewedData sources: HELDA - Digital Repository of the University of HelsinkiGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyUniSA Research Outputs RepositoryArticle . 2019 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/s2352-3018(19)30196-1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 271 citations 271 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!visibility 35visibility views 35 download downloads 105 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6934077Data sources: PubMed CentralFachrepositorium LebenswissenschaftenArticle . 2019License: CC BYData sources: Fachrepositorium Lebenswissenschaftenhttps://hdl.handle.net/10067/1...Article . 2019Data sources: Institutional Repository Universiteit AntwerpenUniversity of Southern Denmark Research OutputArticle . 2019Data sources: University of Southern Denmark Research OutputSpiral - Imperial College Digital RepositoryArticle . 2019Data sources: Spiral - Imperial College Digital RepositoryUniversity of Lincoln Institutional RepositoryArticle . 2019 . Peer-reviewedData sources: University of Lincoln Institutional RepositoryGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyHELDA - Digital Repository of the University of HelsinkiArticle . 2019 . Peer-reviewedData sources: HELDA - Digital Repository of the University of HelsinkiGhent University Academic BibliographyArticle . 2019Data sources: Ghent University Academic BibliographyUniSA Research Outputs RepositoryArticle . 2019 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/s2352-3018(19)30196-1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2018 United KingdomPublisher:Springer Science and Business Media LLC Funded by:WT, NHMRC | Focus on the uterus: basi...WT ,NHMRC| Focus on the uterus: basic and translational research strategies to address key issues in women’s health. Fertility, infertility, endometrial and pregnancy disorders.Authors: Mike Clarke;Mike Clarke;Abstract Six years after the launch of Systematic Reviews by Biomed Central, this article is part of the celebration of the journal. It contains personal reflections on the past, present and future of systematic reviews, using examples relevant to the role of systematic reviews in cataloguing and analysing research, assessing quality and planning new studies. The focus is on the most common of the various types of systematic review in health and social care, namely those assessing the effects of interventions.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6204283Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s13643-018-0833-3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 11 citations 11 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6204283Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s13643-018-0833-3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 United Kingdom, SpainPublisher:Frontiers Media SA Funded by:NHMRC | Uncoupled Research Fellow..., UKRI | Linking electronic health..., WT +4 projectsNHMRC| Uncoupled Research Fellowship ,UKRI| Linking electronic health records with passive smartphone activity data to predict outcomes in psychotic disorders ,WT ,UKRI| What are the clinical and educational risk factors for poor academic outcomes in children with Autistic Spectrum Disorder? ,UKRI| The Alan Turing Institute ,EC| INCA ,UKRI| "Information about Drinking for Ex-serving personnel (InDEx)" - Development of a personalised alcohol appAuthors: Sumithra Velupillai; Sumithra Velupillai; Sumithra Velupillai; Gergö Hadlaczky; +21 AuthorsSumithra Velupillai; Sumithra Velupillai; Sumithra Velupillai; Gergö Hadlaczky; Gergö Hadlaczky; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Enrique Baca-Garcia; Genevieve M. Gorrell; Nomi Werbeloff; Dong Nguyen; Dong Nguyen; Rashmi Patel; Rashmi Patel; Daniel Leightley; Johnny Downs; Johnny Downs; Matthew Hotopf; Matthew Hotopf; Rina Dutta; Rina Dutta;pmc: PMC6381841
pmid: 30814958
This manuscript was written as a result of a workshop that was held at the Institute of Psychiatry, Psychology and Neuroscience, King’s College London, financially supported by the European Science Foundation (ESF) Research Networking Programme Evaluating Information Access Systems: http://elias-network.eu/. SV is supported by the Swedish Research Council (2015-00359) and the Marie Skłodowska Curie Actions, Cofund, Project INCA 600398. EB-G is partially supported by grants from Instituto de Salud Carlos III (ISCIII PI13/02200; PI16/01852), Delegación del Gobierno para el Plan Nacional de Drogas (20151073); American Foundation for Suicide Prevention (AFSP) (LSRG- 1-005-16). NW is supported by the UCLH NIHR Biomedical Research Centre. DN is supported by The Alan Turing Institute under the EPSRC grant EP/N510129/1, with an Alan Turing Institute Fellowship (TU/A/000006). RP has received support from a Medical Research Council (MRC) Health Data Research UK Fellowship (MR/S003118/1) and a Starter Grant for Clinical Lecturers (SGL015/1020) supported by the Academy of Medical Sciences, The Wellcome Trust, MRC, British Heart Foundation, Arthritis Research UK, the Royal College of Physicians and Diabetes UK. DL is supported by the UK Medical Research Council under grant MR/N028244/2 and the King’s Centre for Military Health Research. JD is supported by a Medical Research Council (MRC) Clinical Research Training Fellowship (MR/L017105/1). RD is funded by a Clinician Scientist Fellowship (research project e-HOST-IT) from the Health Foundation in partnership with the Academy of Medical Sciences Risk assessment of suicidal behavior is a time-consuming but notoriously inaccurate activity formental health services globally. In the last 50 years a large number of tools have been designed for suicide risk assessment, and tested in a wide variety of populations, but studies show that these tools suffer fromlow positive predictive values.More recently, advances in research fields such as machine learning and natural language processing applied on large datasets have shown promising results for health care, and may enable an important shift in advancing precision medicine. In this conceptual review, we discuss established risk assessment tools and examples of novel data-driven approaches that have been used for identification of suicidal behavior and risk. We provide a perspective on the strengths and weaknesses of these applications to mental health-related data, and suggest research directions to enable improvement in clinical practice
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6381841Data sources: PubMed CentralRecolector de Ciencia Abierta, RECOLECTAArticle . 2019Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3389/fpsyt.2019.00036&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 46 citations 46 popularity Top 1% influence Top 10% impulse Top 10% Powered by BIP!visibility 5visibility views 5 download downloads 100 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6381841Data sources: PubMed CentralRecolector de Ciencia Abierta, RECOLECTAArticle . 2019Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3389/fpsyt.2019.00036&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2020 Turkey, Turkey, France, Netherlands, United Kingdom, TurkeyPublisher:American Society of Hematology Funded by:NHMRC | Delineating aberrant adap..., EC | iDysChart, FWF | Novel immunodeficiency un... +1 projectsNHMRC| Delineating aberrant adaptive immune responses due to germline mutations in the PI3K signalling pathway ,EC| iDysChart ,FWF| Novel immunodeficiency unravels immune homeostasis mechanism ,WT| The immunopathogenesis of Epstein-Barr virus-associated malignancies.Sujal Ghosh; Sevgi Köstel Bal; Emily S.J. Edwards; Bethany Pillay; Raúl Jiménez Heredia; Funda Erol Cipe; Geetha Rao; Elisabeth Salzer; Samaneh Zoghi; Hassan Abolhassani; Tooba Momen; Emma Gostick; David Price; Yu Zhang; Andrew J. Oler; Claudia Gonzaga-Jauregui; Baran Erman; Ayse Metin; Inci Ilhan; Sule Haskologlu; Candan Islamoglu; Kubra Baskin; Serdar Ceylaner; Ebru Yilmaz; Ekrem Unal; Musa Karakukcu; Dagmar Berghuis; Theresa Cole; Aditya Gupta; Fabian Hauck; Hubert Kogler; Andy I. M. Hoepelman; Safa Baris; Elif Karakoc-Aydiner; Ahmet Ozen; Leo Kager; Dirk Holzinger; Michael Paulussen; Renate Krüger; Roland Meisel; Prasad T. Oommen; Emma C. Morris; Bénédicte Neven; Austen Worth; Joris M. van Montfrans; Pieter L. A. Fraaij; Sharon Choo; Figen Dogu; E. Graham Davies; Siobhan O. Burns; Gregor Dückers; Ruy Perez Becker; Horst von Bernuth; Sylvain Latour; Maura Faraci; Marco Gattorno; Helen C. Su; Qiang Pan-Hammarström; Lennart Hammarström; Michael J. Lenardo; Cindy S. Ma; Tim Niehues; Asghar Aghamohammadi; Nima Rezaei; Aydan Ikinciogullari; Stuart G. Tangye; Arjan C. Lankester; Kaan Boztug; Ebmt;pmc: PMC7735164
handle: 1887/3184827 , 11424/243206
Abstract Biallelic mutations in the genes encoding CD27 or its ligand CD70 underlie inborn errors of immunity (IEIs) characterized predominantly by Epstein-Barr virus (EBV)-associated immune dysregulation, such as chronic viremia, severe infectious mononucleosis, hemophagocytic lymphohistiocytosis (HLH), lymphoproliferation, and malignancy. A comprehensive understanding of the natural history, immune characteristics, and transplant outcomes has remained elusive. Here, in a multi-institutional global collaboration, we collected the clinical information of 49 patients from 29 families (CD27, n = 33; CD70, n = 16), including 24 previously unreported individuals and identified a total of 16 distinct mutations in CD27, and 8 in CD70, respectively. The majority of patients (90%) were EBV+ at diagnosis, but only ∼30% presented with infectious mononucleosis. Lymphoproliferation and lymphoma were the main clinical manifestations (70% and 43%, respectively), and 9 of the CD27-deficient patients developed HLH. Twenty-one patients (43%) developed autoinflammatory features including uveitis, arthritis, and periodic fever. Detailed immunological characterization revealed aberrant generation of memory B and T cells, including a paucity of EBV-specific T cells, and impaired effector function of CD8+ T cells, thereby providing mechanistic insight into cellular defects underpinning the clinical features of disrupted CD27/CD70 signaling. Nineteen patients underwent allogeneic hematopoietic stem cell transplantation (HSCT) prior to adulthood predominantly because of lymphoma, with 95% survival without disease recurrence. Our data highlight the marked predisposition to lymphoma of both CD27- and CD70-deficient patients. The excellent outcome after HSCT supports the timely implementation of this treatment modality particularly in patients presenting with malignant transformation to lymphoma.
NARCIS arrow_drop_down NARCIS; BloodOther literature type . Article . 2020 . Peer-reviewedİstinye University Institutional RepositoryArticle . 2020Data sources: İstinye University Institutional RepositoryMarmara University Open Access SystemArticle . 2020Data sources: Marmara University Open Access SystemUniversitätsbibliographie, Universität Duisburg-EssenArticle . 2020Data sources: Universitätsbibliographie, Universität Duisburg-EssenNARCIS; BloodArticle . 2020Mémoires en Sciences de l'Information et de la CommunicationArticle . 2020Full-Text: https://hal.science/hal-03066024/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1182/blood.2020007763&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 66 citations 66 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert NARCIS arrow_drop_down NARCIS; BloodOther literature type . Article . 2020 . Peer-reviewedİstinye University Institutional RepositoryArticle . 2020Data sources: İstinye University Institutional RepositoryMarmara University Open Access SystemArticle . 2020Data sources: Marmara University Open Access SystemUniversitätsbibliographie, Universität Duisburg-EssenArticle . 2020Data sources: Universitätsbibliographie, Universität Duisburg-EssenNARCIS; BloodArticle . 2020Mémoires en Sciences de l'Information et de la CommunicationArticle . 2020Full-Text: https://hal.science/hal-03066024/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1182/blood.2020007763&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2020 Finland, Italy, ItalyPublisher:Springer Science and Business Media LLC Funded by:NIH | VITAMIN INTERVENTION FOR ..., NIH | Genetics of ischemic stro..., WT | Understanding the genetic... +19 projectsNIH| VITAMIN INTERVENTION FOR STROKE PREVENTION ,NIH| Genetics of ischemic stroke in the SiGN Consortium ,WT| Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics. ,NHMRC| Australian Stroke Genetics Collaborative - Genome-wide association study in ischaemic stroke ,NIH| THE BALTIMORE LONGITUDINAL STUDY OF HUMAN AGING ,NIH| ISGS: The Ischemic Stroke Genetics Study ,NIH| MULTICENTERED STUDY OF STROKE GENETICS ,NIH| Genetic Risk to Stroke in Smokers and Nonsmokers in Two Ethnic Groups ,NIH| Genetics Of Stroke ,EC| GEUVADIS ,NIH| Data Mgmt &Analysis Core - The NINDS International Stroke Genetics Consortium St ,WT| A genome wide association study in ischaemic stroke. ,NIH| GWAS of Hormone Treatment and CVD and Metabolic Outcomes in the WHI ,NIH| A Center for GEI Association Studies ,NIH| Genetics of Early Onset-Stroke ,NIH| Genome Wide Association Coordinating Center ,NIH| Genetics of Early-Onset Ischemic Stroke Consortium ,NIH| Research Training in the Epidemiology of Aging ,WT| WTCCC2 core activities ,NIH| CORE--ADIPOSE TISSUE BIOLOGY AND BASIC MECHANISMS ,NIH| Randomized Clinical Trials - Whole Genome Studies Coordinating Center ,NIH| A Genome-wide Association Study for Early-Onset Myocardial InfarctionAuthors: Stefano Mammola; Diego Fontaneto; Alejandro Martínez; Filipe Chichorro;Stefano Mammola; Diego Fontaneto; Alejandro Martínez; Filipe Chichorro;handle: 10138/326141
Many believe that the quality of a scientific publication is as good as the science it cites. However, quantifications of how features of reference lists affect citations remain sparse. We examined seven numerical characteristics of reference lists of 50,878 research articles published in 17 ecological journals between 1997 and 2017. Over this period, significant changes occurred in reference lists' features. On average, more recent papers have longer reference lists and cite more high Impact Factor papers and fewer non-journal publications. We also show that highly cited articles across the ecological literature have longer reference lists, cite more recent and impactful references, and include more self-citations. Conversely, the proportion of 'classic' papers and non-journal publications cited, as well as the temporal span of the reference list, have no significant influence on articles' citations. From this analysis, we distill a recipe for crafting impactful reference lists, at least in ecology. Peer reviewed
CNR ExploRA arrow_drop_down HELDA - Digital Repository of the University of HelsinkiArticle . 2021 . Peer-reviewedData sources: HELDA - Digital Repository of the University of Helsinkiadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11192-020-03759-0&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routeshybrid 28 citations 28 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert CNR ExploRA arrow_drop_down HELDA - Digital Repository of the University of HelsinkiArticle . 2021 . Peer-reviewedData sources: HELDA - Digital Repository of the University of Helsinkiadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11192-020-03759-0&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2015Publisher:Elsevier BV Funded by:WT | Thai health-risk transist..., NHMRC | Thai Health-Risk Transiti..., NHMRC | Thai health-risk transiti...WT| Thai health-risk transistion: Anational cohort study. ,NHMRC| Thai Health-Risk Transition: a National Cohort Study - Phase II ,NHMRC| Thai health-risk transition: a national cohort studyWimalin Rimpeekool; Sam-ang Seubsman; Cathy Banwell; Martyn D. Kirk; Vasoontara Yiengprugsawan; Adrian Sleigh;This paper reviews the evolution of Thai food and nutrition label policies and Thailand’s international role relating to food product safety and standards. The historical record has been interpreted to identify future trends and challenges related to food labelling. These challenges are arising in Thailand and many similar emerging economies. Thailand has a good reputation in world food markets and is now becoming a global leader in food production and export. It has become deeply involved with regulations and standards applied by World Trade Organization and Codex Alimentarius while serving its own population with a safe and secure food supply. For consumers considering Thai food products, food labels can provide useful nutrition information and help build trust. Thais began a century ago with policies and laws to enhance food safety and to protect Thai consumers. During the lengthy journey from national to global standards Thai food labels have evolved and now contribute to international food labelling policies. This contribution comes from the perspective of a leading middle income south-east Asian food producer now trading with high income countries around the world. The story of that journey – a case study for many other countries in a similar situation – has not previously been told. This article provides information for policy makers dealing with food labelling, embedding trends and tensions for one middle income food exporter in a long history. Information captured here should be helpful for other middle income countries, especially those with limited records. This strategic knowledge will enable better decisions for future policies. Highlights • Thai food labels show transition from closed agriculture to global agribusiness • Thai food quality follows investment in food science and technology after WW2 • Thai food labels address transition from hunger to plenty and international rules • It is difficult to harmonize nutrition labels among the countries of SE Asia • Domestic protection versus global food trade creates tension and new rules
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4608433Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.foodpol.2015.07.011&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 28 citations 28 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4608433Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.foodpol.2015.07.011&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu