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Digital Humanities and Cultural Heritage
2018-2022
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Academy of Finland
An omics approach to identify envir...

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Supplementary Table of GLM results from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs
Research datakeyboard_double_arrow_right Dataset 2022Publisher:The Royal SocietyFunded by:AKA | An omics approach to iden...
AKA| An omics approach to identify environmental, metabolic and genomic determinants of canine neurobehavioral traits as natural models of human anxiety
Authors: Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; +1 Authors
Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; Lohi, Hannes;
doi: 10.6084/m9.figshare.19149504 , 10.6084/m9.figshare.19149504.v1
doi: 10.6084/m9.figshare.19149504 , 10.6084/m9.figshare.19149504.v1
Supplementary Tables in excel-format describing the detailed results of GLM models for each measurand.
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Supplementary Table of AIC model selection from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs
Research datakeyboard_double_arrow_right Dataset 2022Publisher:The Royal SocietyFunded by:AKA | An omics approach to iden...
AKA| An omics approach to identify environmental, metabolic and genomic determinants of canine neurobehavioral traits as natural models of human anxiety
Authors: Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; +1 Authors
Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; Lohi, Hannes;
doi: 10.6084/m9.figshare.19149498.v1 , 10.6084/m9.figshare.19149498
doi: 10.6084/m9.figshare.19149498.v1 , 10.6084/m9.figshare.19149498
Supplementary Tables in excel-format describing the AIC model selection process for each measurand in GLM analyses.
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Supplementary material from "Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs"
Research datakeyboard_double_arrow_right Collection 2022Publisher:The Royal SocietyFunded by:AKA | An omics approach to iden...
AKA| An omics approach to identify environmental, metabolic and genomic determinants of canine neurobehavioral traits as natural models of human anxiety
Authors: Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; +1 Authors
Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; Lohi, Hannes;
doi: 10.6084/m9.figshare.c.5834289 , 10.6084/m9.figshare.c.5834289.v1
doi: 10.6084/m9.figshare.c.5834289 , 10.6084/m9.figshare.c.5834289.v1
As an individual's metabolism reflects health and disease states well, metabolomics holds a vast potential in biomedical applications. However, normal physiological factors, such as age, can also influence metabolism, challenging the establishment of disease-specific metabolic aberrations. Here, we examined how physiological and diet-related factors drive variance in the metabolism of healthy pet dogs. We analysed 2068 serum samples using a canine nuclear magnetic resonance (NMR) spectroscopy-based metabolomics platform. With generalized linear models, we discovered that age, breed, sex, sterilization, diet type and fasting time significantly affected the canine metabolite profiles. Especially, breed and age caused considerable variation in the metabolite concentrations, and breeds with very different body conformations systematically differed in several lipid measurands. Our results enhance the understanding how normal physiological factors influence canine metabolism, aid accurate interpretation of the NMR results, and suggest the NMR platform might be applied in identifying aberrations in nutrient absorption and metabolism.
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Collection . 2022
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The following results are related to Digital Humanities and Cultural Heritage. Are you interested to view more results? Visit OpenAIRE - Explore.

Supplementary Table of GLM results from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs
Research datakeyboard_double_arrow_right Dataset 2022Publisher:The Royal SocietyFunded by:AKA | An omics approach to iden...
AKA| An omics approach to identify environmental, metabolic and genomic determinants of canine neurobehavioral traits as natural models of human anxiety
Authors: Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; +1 Authors
Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; Lohi, Hannes;
doi: 10.6084/m9.figshare.19149504 , 10.6084/m9.figshare.19149504.v1
doi: 10.6084/m9.figshare.19149504 , 10.6084/m9.figshare.19149504.v1
Supplementary Tables in excel-format describing the detailed results of GLM models for each measurand.
figsharearrow_drop_down
figshare
Dataset . 2022
License: CC BY
Data sources: Datacite
figshare
Dataset . 2022
License: CC BY
Data sources: Datacite
linkLink to
shareshareShare
citeCite
addClaim
Please grant OpenAIRE to access and update your ORCID works.
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Dataset . 2022
License: CC BY
Data sources: Datacite
figshare
Dataset . 2022
License: CC BY
Data sources: Datacite
linkLink to
shareshareShare
citeCite
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Please grant OpenAIRE to access and update your ORCID works.
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Supplementary Table of AIC model selection from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs
Research datakeyboard_double_arrow_right Dataset 2022Publisher:The Royal SocietyFunded by:AKA | An omics approach to iden...
AKA| An omics approach to identify environmental, metabolic and genomic determinants of canine neurobehavioral traits as natural models of human anxiety
Authors: Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; +1 Authors
Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; Lohi, Hannes;
doi: 10.6084/m9.figshare.19149498.v1 , 10.6084/m9.figshare.19149498
doi: 10.6084/m9.figshare.19149498.v1 , 10.6084/m9.figshare.19149498
Supplementary Tables in excel-format describing the AIC model selection process for each measurand in GLM analyses.
figsharearrow_drop_down
figshare
Dataset . 2022
License: CC BY
Data sources: Datacite
figshare
Dataset . 2022
License: CC BY
Data sources: Datacite
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citeCite
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Dataset . 2022
License: CC BY
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Dataset . 2022
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Please grant OpenAIRE to access and update your ORCID works.
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Supplementary material from "Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs"
Research datakeyboard_double_arrow_right Collection 2022Publisher:The Royal SocietyFunded by:AKA | An omics approach to iden...
AKA| An omics approach to identify environmental, metabolic and genomic determinants of canine neurobehavioral traits as natural models of human anxiety
Authors: Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; +1 Authors
Puurunen, Jenni; Ottka, Claudia; Salonen, Milla; Niskanen, Julia E.; Lohi, Hannes;
doi: 10.6084/m9.figshare.c.5834289 , 10.6084/m9.figshare.c.5834289.v1
doi: 10.6084/m9.figshare.c.5834289 , 10.6084/m9.figshare.c.5834289.v1
As an individual's metabolism reflects health and disease states well, metabolomics holds a vast potential in biomedical applications. However, normal physiological factors, such as age, can also influence metabolism, challenging the establishment of disease-specific metabolic aberrations. Here, we examined how physiological and diet-related factors drive variance in the metabolism of healthy pet dogs. We analysed 2068 serum samples using a canine nuclear magnetic resonance (NMR) spectroscopy-based metabolomics platform. With generalized linear models, we discovered that age, breed, sex, sterilization, diet type and fasting time significantly affected the canine metabolite profiles. Especially, breed and age caused considerable variation in the metabolite concentrations, and breeds with very different body conformations systematically differed in several lipid measurands. Our results enhance the understanding how normal physiological factors influence canine metabolism, aid accurate interpretation of the NMR results, and suggest the NMR platform might be applied in identifying aberrations in nutrient absorption and metabolism.
figsharearrow_drop_down
figshare
Collection . 2022
License: CC BY
Data sources: Datacite
figshare
Collection . 2022
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Collection . 2022
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An omics approach to identify envir...

Supplementary Table of GLM results from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary Table of AIC model selection from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary material from "Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs"

Supplementary Table of GLM results from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary Table of AIC model selection from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary material from "Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs"

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Supplementary Table of GLM results from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary Table of AIC model selection from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary material from "Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs"

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Supplementary Table of GLM results from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary Table of AIC model selection from Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs

Supplementary material from "Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs"

Digital Humanities and Cultural Heritage
2018-2022
Research data
Research software
Academy of Finland
An omics approach to identify envir...