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Research data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:EC | ERAS, NWO | Evolution of astronomical..., EC | EARTHSEQUENCINGEC| ERAS ,NWO| Evolution of astronomically paced climate changes from Greenhouse to Icehouse world ,EC| EARTHSEQUENCINGBeddow, Helen M; Liebrand, Diederik; Wilson, Douglas S; Hilgen, Frederik J; Sluijs, Appy; Wade, Bridget S; Lourens, Lucas Joost;Astronomical tuning of sediment sequences requires both unambiguous cycle-pattern recognition in climate proxy records and astronomical solutions, and independent information about the phase relationship between these two. Here we present two different astronomically tuned age models for the Oligocene-Miocene Transition (OMT) from Integrated Ocean Drilling Program Site U1334 (equatorial Pacific Ocean) to assess the effect tuning has on astronomically calibrated ages and the geologic time scale. These alternative age models (from ~22 to ~24 Ma) are based on different tunings between proxy records and eccentricity: the first age model is based on an aligning CaCO3 weight (wt%) to Earth's orbital eccentricity, the second age model is based on a direct age calibration of benthic foraminiferal stable carbon isotope ratios (d13C) to eccentricity. To independently test which tuned age model and associated tuning assumptions is in best agreement with independent ages based on tectonic plate-pair spreading rates, we assign our tuned ages to the magnetostratigraphic reversals identified in deep-marine magnetic anomaly profiles. Subsequently, we compute tectonic plate-pair spreading rates based on the tuned ages. The resultant, alternative spreading rate histories indicate that the CaCO3 tuned age model is most consistent with a conservative assumption of constant, or linearly changing, spreading rates. The CaCO3 tuned age model thus provides robust ages and durations for polarity chrons C6Bn.1n-C6Cn.1r, which are not based on astronomical tuning in the latest iteration of the Geologic Time Scale. Furthermore, it provides independent evidence that the relatively large (several 10,000 years) time lags documented in the benthic foraminiferal isotope records relative to orbital eccentricity, constitute a real feature of the Oligocene-Miocene climate system and carbon cycle. The age constraints from Site U1334 thus provide independent evidence that the delayed responses of the Oligocene-Miocene climate-cryosphere system and carbon cycle resulted from highly nonlinear feedbacks to astronomical forcing. Supplement to: Beddow, Helen M; Liebrand, Diederik; Wilson, Douglas S; Hilgen, Frederik J; Sluijs, Appy; Wade, Bridget S; Lourens, Lucas Joost (2018): Astronomical tunings of the Oligocene-Miocene transition from Pacific Ocean Site U1334 and implications for the carbon cycle. Climate of the Past, 14(3), 255-270
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.885365&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:NWO | Evolution of astronomical..., UKRI | The paradox of high-ampli..., EC | EARTHSEQUENCINGNWO| Evolution of astronomically paced climate changes from Greenhouse to Icehouse world ,UKRI| The paradox of high-amplitude inter(glacial) variability across the Oligo-Miocene transition tackled using spectacular new deep-sea sediment archives ,EC| EARTHSEQUENCINGLiebrand, Diederik; Raffi, Isabella; Fraguas, Ángela; Laxenaire, Rémi; Bosmans, Joyce H C; Hilgen, Frederik J; Wilson, Paul A; Batenburg, Sietske J; Beddow, Helen M; Bohaty, Steven M; Bown, Paul R; Crocker, Anya J; Huck, Claire E; Lourens, Lucas Joost; Sabia, Luciana;Pelagic sediments from the subtropical South Atlantic Ocean contain geographically extensive Oligocene ooze and chalk layers that consist almost entirely of the calcareous nannofossil Braarudosphaera. Poor recovery and the lack of precise dating of these horizons in previous studies has limited our understanding of the exact number of acmes, their timing and durations, and the causes of their recurrence. Here we present a high-resolution, astronomically tuned stratigraphy of Braarudosphaera oozes (29.5-27.9 Ma) from Ocean Drilling Program Site 1264 in the subtropical southeastern Atlantic Ocean. We identify seven acme events in the Braarudosphaera abundance record. The longest lasting acme event corresponds to a strong minimum in the ~2.4-My eccentricity cycle, and four acme events coincide with ~110-ky and 405-ky eccentricity maxima. We propose that eccentricity-modulated precession forcing of the freshwater budget of the South Atlantic Ocean resulted in the episodic formation of a shallow pycnocline and hyperstratification of the upper water column. We speculate that stratified surface water conditions may have served as a virtual sea floor, which facilitated the widespread Braarudosphaera acmes. This explanation reconciles the contrasting distribution patterns of Braarudosphaera in the modern ocean, limited largely to shallow water coastal settings, compared to their relatively brief and expanded oceanic distribution in the past. Supplement to: Liebrand, Diederik; Raffi, Isabella; Fraguas, Ángela; Laxenaire, Rémi; Bosmans, Joyce H C; Hilgen, Frederik J; Wilson, Paul A; Batenburg, Sietske J; Beddow, Helen M; Bohaty, Steven M; Bown, Paul R; Crocker, Anya J; Huck, Claire E; Lourens, Lucas Joost; Sabia, Luciana (2018): Orbitally Forced Hyperstratification of the Oligocene South Atlantic Ocean. Paleoceanography and Paleoclimatology, 33(5), 511-529
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.878110&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.878110&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Other dataset type , Dataset 2018 EnglishPublisher:PANGAEA Funded by:EC | SINK, NWO | Subduction Initiation rec...EC| SINK ,NWO| Subduction Initiation reconstructed from Neotethyan Kinematics (SINK): An integrated geological and numerical study of the driving forces behind plate tectonicsGürer, Derya; van Hinsbergen, Douwe J J; Özkaptan, Murat; Creton, Iverna; Koymans, Mathijs R; Cascella, Antonio; Langereis, Cornelis G;To quantitatively reconstruct the kinematic evolution of Central and Eastern Anatolia within the framework of Neotethyan subduction accommodating Africa-Eurasia convergence, we paleomagnetically assess timing and amount of vertical axis rotations across the Ulukisla and Sivas regions. We show paleomagnetic results from ~30 localities identifying a coherent rotation of a block - comprising the southern Kirsehir Block, the Ulukisla basin, the Central and Eastern Taurides, and the southern part of the Sivas basin. This block experienced a ~30° counter-clockwise vertical axis rotation since Oligocene time. Sediments in the northern Sivas region show clockwise rotations. We use the rotation patterns together with known fault zones to argue that the counter-clockwise rotating domain of south-central Turkey was bounded by the Savcili Thrust Zone and Deliler-Tecer Fault Zone in the north and by the African-Arabian trench in the south, the western boundary of which is poorly constrained and requires future study. Our new paleomagnetic constraints provide a key ingredient for future kinematic restorations of the Anatolian tectonic collage. We combine our extensive new dataset with existing data (Guerer et al., 2018, and references therein) to identify the dimension of rotating domains in Central and Eastern Anatolia, and identify structures that may have accommodated these rotations. Paleomagnetic interpretations and statistical analyses were carried out using the platform independent portal Paleomagnetism.org (Koymans et al., 2016). Supplement to: Gürer, Derya; van Hinsbergen, Douwe J J; Özkaptan, Murat; Creton, Iverna; Koymans, Mathijs R; Cascella, Antonio; Langereis, Cornelis G (2018): Paleomagnetic constraints on the timing and distribution of Cenozoic rotations in Central and Eastern Anatolia. Solid Earth, 9(2), 295-322
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceOther dataset type . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.887421&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu1 citations 1 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceOther dataset type . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.887421&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2011 EnglishPublisher:PANGAEA Funded by:EC | DINOPRO, NWO | Biotic, climatic and geoc..., EC | PACEMAKEREC| DINOPRO ,NWO| Biotic, climatic and geochemical change during Early Eocene transient global warming events ,EC| PACEMAKERSluijs, Appy; Bijl, Peter K; Schouten, Stefan; Röhl, Ursula; Reichart, Gert-Jan; Brinkhuis, Henk;A brief (~150 kyr) period of widespread global average surface warming marks the transition between the Paleocene and Eocene epochs, ~56 million years ago. This so-called "Paleocene-Eocene thermal maximum" (PETM) is associated with the massive injection of 13C-depleted carbon, reflected in a negative carbon isotope excursion (CIE). Biotic responses include a global abundance peak (acme) of the subtropical dinoflagellate Apectodinium. Here we identify the PETM in a marine sedimentary sequence deposited on the East Tasman Plateau at Ocean Drilling Program (ODP) Site 1172 and show, based on the organic paleothermometer TEX86, that southwest Pacific sea surface temperatures increased from ~26 °C to ~33°C during the PETM. Such temperatures before, during and after the PETM are >10 °C warmer than predicted by paleoclimate model simulations for this latitude. In part, this discrepancy may be explained by potential seasonal biases in the TEX86 proxy in polar oceans. Additionally, the data suggest that not only Arctic, but also Antarctic temperatures may be underestimated in simulations of ancient greenhouse climates by current generation fully coupled climate models. An early influx of abundant Apectodinium confirms that environmental change preceded the CIE on a global scale. Organic dinoflagellate cyst assemblages suggest a local decrease in the amount of river run off reaching the core site during the PETM, possibly in concert with eustatic rise. Moreover, the assemblages suggest changes in seasonality of the regional hydrological system and storm activity. Finally, significant variation in dinoflagellate cyst assemblages during the PETM indicates that southwest Pacific climates varied significantly over time scales of 103 - 104 years during this event, a finding comparable to similar studies of PETM successions from the New Jersey Shelf. Supplement to: Sluijs, Appy; Bijl, Peter K; Schouten, Stefan; Röhl, Ursula; Reichart, Gert-Jan; Brinkhuis, Henk (2011): Southern ocean warming, sea level and hydrological change during the Paleocene-Eocene thermal maximum. Climate of the Past, 7(1), 47-61
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceDataset . Collection . 2011License: CC BYPANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2011License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.756399&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceDataset . Collection . 2011License: CC BYPANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2011License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.756399&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:NWO | Perturbations of System E..., EC | DIOLSNWO| Perturbations of System Earth: Reading the Past to Project the Future - A proposal to create the Netherlands Earth System Science Centre (ESSC) ,EC| DIOLSde Bar, Marijke W; Stolwijk, Dave; McManus, Jerry F; Sinninghe Damsté, Jaap S; Schouten, Stefan;In this study we have applied different indices based on long chain diols, i.e., the Long chain Diol Index (LDI) as proxy for past SST, the Diol Index as indicator of past upwelling conditions and the Nutrient Diol Index (NDI) as proxy for nitrate and phosphate concentrations in seawater. The proxies were analyzed in marine sediments recovered at ODP Site 1234, located within the Peru-Chile upwelling system, with a 2 kyr resolution, covering the last 150 kyrs. We also generated TEX^H^~86 and U_K'37 temperature and planktonic δ^18^O records, as well as total organic carbon (TOC) and accumulation rates (ARs) of TOC and lipid biomarkers (i.e., C~37~ alkenones, GDGTs, dinosterol and loliolide) to reconstruct past phytoplankton production. The LDI-derived SST record co-varies with TEX^H^86- and UK'37-derived SST records as well as with the planktonic δ^18^O record, implying that the LDI reflects past SST variations at this site. TOC and phytoplankton AR records indicate increased export production during the Last Interglacial (MIS 5), simultaneous with a peak in the abundance of preserved _Chaetoceros diatoms, suggesting intensified upwelling during this period. The Diol Index is relatively low during the upwelling period, but peaks before and after this period, suggesting that Proboscia diatoms were more abundant before and after the period of upwelling. The NDI reveals the same trends as the Diol Index suggesting that the input of nitrate and phosphate was minimal during upwelling, which is unrealistic. We suggest that the Diol Index and NDI should perhaps be considered as indicators for Proboscia productivity instead of upwelling conditions or nutrient concentrations. Supplement to: de Bar, Marijke W; Stolwijk, Dave; McManus, Jerry F; Sinninghe Damsté, Jaap S; Schouten, Stefan (2018): A Late Quaternary climate record based on long-chain diol proxies from the Chilean margin. Climate of the Past, 14(11), 1783-1803
PANGAEA arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.892652&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.892652&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:NWO | A sensitive ultra high pr..., EC | DINOPRONWO| A sensitive ultra high pressure liquid chromatography - mass spectrometer to unlock high-resolution climate archives ,EC| DINOPROFrieling, Joost; Reichart, Gert-Jan; Middelburg, Jack J; Röhl, Ursula; Westerhold, Thomas; Bohaty, Steven M; Sluijs, Appy;The Paleocene - Eocene Thermal Maximum (PETM; 56 Ma) was a phase of rapid global warming associated with massive carbon input into the ocean-atmosphere system from a 13C-depleted reservoir. Many mid- and high-latitude sections have been studied and document changes in salinity, hydrology and sedimentation, deoxygenation, biotic overturning and migrations, but detailed records from tropical regions are lacking. Here, we study the PETM at Ocean Drilling Program (ODP) Site 959 in the equatorial Atlantic using a range of organic and inorganic proxies and couple these with dinoflagellate cyst (dinocyst) assemblage analysis. The PETM at Site 959 was previously found to be marked by a ~3.8 per mil negative carbon isotope excursion (CIE), and a ~4 ºC surface ocean warming from the uppermost Paleocene to peak PETM, of which ~1 ºC occurs before the onset of the CIE. We record upper Paleocene dinocyst assemblages that are similar to PETM assemblages as found in extra-tropical regions, confirming poleward migrations of ecosystems during the PETM. The early stages of the PETM are marked by a typical acme of the tropical genus Apectodinium, which reaches abundances of up to 95 %. Subsequently, dinocyst abundances diminish greatly, as do carbonate and pyritized silicate microfossils. The combined paleoenvironmental information from Site 959 and a close by shelf site in Nigeria implies the general absence of eukaryotic surface-dwelling microplankton during peak PETM warmth is most likely caused by heat stress. Crucially, abundant organic benthic foraminiferal linings imply sustained export production, likely driven by prokaryotes. In sharp contrast, the recovery of the CIE yields rapid (<<10 kyr) fluctuations in the abundance of several dinocyst groups, suggesting extreme ecosystem and environmental variability. Supplement to: Frieling, Joost; Reichart, Gert-Jan; Middelburg, Jack J; Röhl, Ursula; Westerhold, Thomas; Bohaty, Steven M; Sluijs, Appy (2018): Tropical Atlantic climate and ecosystem regime shifts during the Paleocene-Eocene Thermal Maximum. Climate of the Past, 14(1), 39-55
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 2022Publisher:figshare Funded by:EC | COGS, NWO | BBMRI-NL, EC | BRIDGES +4 projectsEC| COGS ,NWO| BBMRI-NL ,EC| BRIDGES ,NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,NIH| Shared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa Pedigrees ,NIH| Breast Cancer Family Registry Cohort ,EC| B-CASTGiardiello, Daniele; Hooning, Maartje J.; Hauptmann, Michael; Keeman, Renske; Heemskerk-Gerritsen, B. A. M.; Becher, Heiko; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Camp, Nicola J.; Czene, Kamila; Devilee, Peter; Eccles, Diana M.; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; García-Closas, Montserrat; Haiman, Christopher A.; Hamann, Ute; Hopper, John L.; Jakubowska, Anna; Leeuwen, Floor E.; Lindblom, Annika; Lubiński, Jan; Margolin, Sara; Martinez, Maria Elena; Nevanlinna, Heli; Nevelsteen, Ines; Pelders, Saskia; Pharoah, Paul D. P.; Siesling, Sabine; Southey, Melissa C.; van der Hout, Annemieke H.; van Hest, Liselotte P.; Chang-Claude, Jenny; Hall, Per; Easton, Douglas F.; Steyerberg, Ewout W.; Schmidt, Marjanka K.;Additional file 2: Table S1. Description of the studies included in the analyses.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 1999 EnglishPublisher:Inter-university Consortium for Political and Social Research (ICPSR) Funded by:NIH | TRAINING IN RESEARCH ON M..., NIH | Midlife Health in Japan (..., AKA | Work stress and risk of c... +92 projectsNIH| TRAINING IN RESEARCH ON MENTAL HEALTH AND AGING ,NIH| Midlife Health in Japan (MIDJA) and the U.S. (MIDUS) ,AKA| Work stress and risk of coronary heart disease: Does a healthy life style eliminate the adverse effect? Pooled analysis of 6 major prospective cohort studies from Europe ,NHMRC| The Older Australian Twins Study (OATS) of healthy brain ageing and age-related neurocognitive disorders ,NIH| Daily Stress and Well-Being during Adulthood ,CIHR ,NIH| SOCIAL AND OCCUPATIONAL INFLUENCES ON HEALTH AND ILLNESS ,AKA| Oxygenology of soil ,NIH| Gene-Environment Interplay of Social Contexts and Aging-Related Outcomes ,NIH| Postdoctoral Training in Geriatric Psychiatry Research ,NIH| ORIGINS OF VARIANCE IN THE OLD-OLD: OCTOGENARIAN TWINS ,NIH| Self-regulation as a Health-Protective Factor in Adverse Socioeconomic Conditions ,NIH| Health behaviors over the adult lifecourse and cognitive aging ,NIH| GENETIC &ENVIRONMENTAL INFLUENCES--BIOBEHAVIORAL AGING ,NIH| Sexuality, Aging and Heart Disease: Translating from Population to Patient ,NIH| Wisconsin Longitudinal Study: Tracking the Life Course ,NIH| OLDEST-OLD MORTALITY AND DISABILITY AMONG DANISH TWINS ,NIH| Stress, Aging and Working Memory ,NIH| CONTROL BELIEFS, MEMORY, AND AGING ,NIH| Biological Embedding of Early-Life SES ,UKRI| Offshore Platform for Energy Competitiveness (OPEC) ,AKA| Genomic epidemiology of addictions and their consequences - national, Nordic and international dimensions. ,AKA| Work, well-being and health - a life course perspective: British arm of Academy of Finland consortia 10190 and 10187 / Consortium: ELRFWCDD ,AKA| Genomic epidemiology of addictions and their consequences - national, Nordic and international dimensions ,NIH| Sleep and Divorce: Identifying Bidirectional Vulnerability and Resilience ,NIH| CTSA INFRASTRUCTURE FOR CLINICAL TRIALS ,NIH| Sex differences in the relationship between APOE and AD: Role of sexual differentiation ,NIH| GENETIC AND ENVIRONMENTAL INFLUENCES IN BEHAVIORAL AGING ,NIH| SES health gradients in late life: testing models of gene-environment interplay in an international twin consortium ,NIH| Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortium ,NIH| Risk for Alzheimer's Disease and Cognitive Decline in Project TALENT ,NIH| Optimizing Couple-Oriented Interventions for Chronic Illness ,NIH| Implementing World Health Assembly Resolution 60.26 ???Workers' Health: Global Pl ,ARC| Discovery Projects - Grant ID: DP200100876 ,AKA| Center of Excellence in Complex Disease Genetics-from Discovery to Precision Medicine / Consortium: CoECDG ,NIH| Integrative Pathways to Health and Illness ,NIH| Personality and Well-Being Trajectories in Adulthood ,NIH| CHANGES IN HEALTH--SOCIOECONOMIC STATUS AND PATHWAYS ,NIH| 1995 SUMMER INSTITUTE IN GERIATRIC MEDICINE ,NIH| AGING AND INTRAINDIVIDUAL COGNITIVE VARIABILITY ,NIH| CORE--PROGRAM DEVELOPMENT ,NHMRC| Gene-environment interaction in healthy brain ageing and age related neurodegeneration ,AKA| Center of Excellence in Complex Disease Genetics ,NIH| DEMOGRAPHY ,NIH| Integrative Pathways to Health and Illness ,SSHRC ,AKA| CoE in Complex Disease Genetics ,NIH| Integrative Analysis of Change in Cognition and Health ,NIH| UCLA OLDER AMERICANS INDEPENDENCE CENTER ,NHMRC| Australian Centre of Excellence in Twin Research ,NHMRC| The genetic and environmental determinants of amyloid deposition in older individuals: an amyloid imaging study using the twin design ,NIH| The VETSA Longitudinal MRI Twin Study of Aging ,AKA| Determinants of Early Exit from Work Force: An International Multicohort Study. ,NIH| Daily stressor reactivity and profiles of physical health across adulthood ,NIH| Genes, Enivronment and the Adjustment of Family Members ,AKA| Determinants of labour market participation and prognosis of common chronic diseases in working populations: a study of cohorts in Finland, United Kingdom and France ,NSF| IBSS: Understanding Long-Term Effects on Children in Economic Distress ,AKA| Heterogeneity of depression at symptom level: Specific versus general patterns in etiology, development, and disability ,NIH| Infrastructure for the Office of Population Research ,NIH| Histories of Social Engagement and Cognitive Functioning ,NIH| Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African Americans ,NIH| WISCONSIN LONGITUDINAL STUDY ,EC| ENGAGE ,NIH| The Population Research Institute ,NWO| Genetische en omgevingsinvloeden op psychopathologie en geluk tijdens de adolescentie ,NIH| TWIN STUDY OF NORMAL AGING ,AKA| Midlife predictors of dementia, frailty and disability at older ages ,NIH| A Longitudinal Twin Study of Cognition and Personality ,NIH| Biopsychosocial Pathways to Type 2 Diabetes ,NIH| Integrative Pathways to Health and Illness ,NWO| A Twin-sibling Study of Adolescent Wellness ,NIH| The VETSA Longitudinal Twin Study of Cortisol and Aging ,NIH| Informing anti-tobacco communications with affective and decision science: Application of the Appraisal Tendency Framework ,NIH| The Greatest Generation: The NAS-NRC WWII Twin Registry as a Scientific Resource ,NIH| A 55-Year Follow-up Study of Project TALENT Twins and Siblings ,AKA| Genetic and environmental predictors of tobacco, drug and alcohol addiction in adolescence and young adulthood ¿ a lifecourse twin and population approach / Consortium: addictgene ,NIH| Aging, Emotional Well-being, and Physical Health ,NIH| AGING AND HEALTH TRAJECTORIES AMONG BLACK &WHITE ADULTS ,NIH| GCRC ,NIH| MEASUREMENT OF ESTRADIOL AND OTHER RELATED HORMONES BY TANDEM MASS SPECTROSCOPY ,NIH| Social Regulation of Gene Expression ,NIH| HEALTH AND PSYCHOSOCIAL FACTORS IN OLDER BLACK TWINS ,UKRI| RootDetect: Remote Detection and Precision Management of Root Health ,NIH| A Longitudinal Twin Study of Cognition and Aging ,NIH| Social and Economic Analysis of Demographic Change ,NIH| Research Training Program in the Behavioral and Biomedical Sciences ,UKRI| Centre for Cognitive Ageing & Cognitive Epidemiology ,AKA| Determinants of labour market participation and prognosis of common chronic diseases in working populations: a study of cohorts in Finland, United Kingdom and France ,AKA| Indicators of marginalization - Role of cognition, substance use and mental health disorders: Longitudinal studies from childhood to end of adolescence ,NIH| Causal Effects of Schooling on Adult and Child Health ,NIH| Institutional Clinical and Translational Science Award ,NIH| Genetic Moderators of Divorce Adjustment: A Pilot Investigation ,NIH| Bio-social Determinants of Fertility &Related Behaviors ,NIH| IMSD Program at Wayne State University ,AKA| Predictors, neuropsychological correlates, and consequences of cannabis and alcohol use among Finnish young adults. A twin and population approachBrim, Orville Gilbert; Baltes, Paul B.; Bumpass, Larry L.; Cleary, Paul D.; Featherman, David L.; Hazzard, William R.; Kessler, Ronald C.; Lachman, Margie E.; Markus, Hazel Rose; Marmot, Michael G.; Rossi, Alice S.; Ryff, Carol D.; Shweder, Richard A.;doi: 10.3886/icpsr02760.v11 , 10.3886/icpsr02760.v1 , 10.3886/icpsr02760.v17 , 10.3886/icpsr02760.v5 , 10.3886/icpsr02760.v10 , 10.3886/icpsr02760.v19 , 10.3886/icpsr02760.v14 , 10.3886/icpsr02760.v7 , 10.3886/icpsr02760.v8 , 10.3886/icpsr02760.v16 , 10.3886/icpsr02760.v12 , 10.3886/icpsr02760.v4 , 10.3886/icpsr02760.v13 , 10.3886/icpsr02760.v6 , 10.3886/icpsr02760.v3 , 10.3886/icpsr02760.v18 , 10.3886/icpsr02760.v15 , 10.3886/icpsr02760.v2 , 10.3886/icpsr02760.v9 , 10.3886/icpsr02760
doi: 10.3886/icpsr02760.v11 , 10.3886/icpsr02760.v1 , 10.3886/icpsr02760.v17 , 10.3886/icpsr02760.v5 , 10.3886/icpsr02760.v10 , 10.3886/icpsr02760.v19 , 10.3886/icpsr02760.v14 , 10.3886/icpsr02760.v7 , 10.3886/icpsr02760.v8 , 10.3886/icpsr02760.v16 , 10.3886/icpsr02760.v12 , 10.3886/icpsr02760.v4 , 10.3886/icpsr02760.v13 , 10.3886/icpsr02760.v6 , 10.3886/icpsr02760.v3 , 10.3886/icpsr02760.v18 , 10.3886/icpsr02760.v15 , 10.3886/icpsr02760.v2 , 10.3886/icpsr02760.v9 , 10.3886/icpsr02760
The Midlife in the United States (MIDUS) is a collaborative, interdisciplinary investigation of patterns, predictors, and consequences of midlife development in the areas of physical health, psychological well-being, and social responsibility. A description of the study and findings from it are available at http://www.midus.wisc.edu. The first wave of the MIDUS study (MIDUS 1 or M1) collected survey data from a total of 7,108 participants. The baseline sample was comprised of individuals from four subsamples: (1) a national RDD (random digit dialing) sample (n=3,487); (2) oversamples from five metropolitan areas in the U.S. (n=757); (3) siblings of individuals from the RDD sample (n=950); and (4) a national RDD sample of twin pairs (n=1,914). All eligible participants were non-institutionalized, English-speaking adults in the coterminous United States, aged 25 to 74. Data from the samples were collected primarily in 1995/96. The survey (Project 1) dataset contains responses from a 30-minute Phone interview and two 50-page Self-Administered Questionnaire (SAQ) instruments. Of the 7,108 respondents who completed the Phone interview, 6,325 also completed the SAQ. This updated version of the study is comprised of three primary datasets: Dataset 1, Main, Siblings, and Twin Data, contains responses from the main survey of 7,108 respondents. Respondents were asked to provide extensive information on their physical and mental health throughout their adult lives, and to assess the ways in which their lifestyles, including relationships and work-related demands, contributed to the conditions experienced. Those queried were asked to describe their histories of physical ailments, including heart-related conditions and cancer, as well as the treatment and/or lifestyle changes they went through as a result. A series of questions addressed alcohol, tobacco, and illegal drug use, and focused on history of use, regularity of use, attempts to quit, and how the use of those substances affected respondents' physical and mental well-being. Additional questions addressed respondents' sense of control over their health, their awareness of changes in their medical conditions, commitment to regular exercise and a healthy diet, experience with menopause, the decision-making process used to deal with health concerns, experiences with nontraditional remedies or therapies, and history of attending support groups. Respondents were asked to compare their overall well-being with that of their peers and to describe social, physical, and emotional characteristics typical of adults in their 20's, 40's, and 60's. Information on the work histories of respondents and their significant others was also elicited, with items covering the nature of their occupations, work-related physical and emotional demands, and how their personal health had correlated to their jobs. An additional series of questions focusing on childhood queried respondents regarding the presence/absence of their parents, religion, rules/punishments, love/affection, physical/verbal abuse, and the quality of their relationships with their parents and siblings. Respondents were also asked to consider their personal feelings of accomplishment, desire to learn, sense of control over their lives, interests, and hopes for the future. The Datasets previously numbered 2 and 3 have been removed to avoid redundancies, and all datasets have been renumbered. Please refer to the readme file. Dataset 2, Twin Screener Data, provides the first national sample of twin pairs ascertained randomly via the telephone. Dataset 3, Coded Text Responses, describes how open-ended textual responses in the MIDUS 1 Computer-Assisted Telephone Interview (CATI) and Self-Administered Questionnaire (SAQ) were transformed into categorical numeric codes. These codes are included in a stand-alone dataset containing only those cases (N=3,950) that contained text data in their responses. Online Analysis Only: Datasets 1, 2, and 3 were merged together by the SU_ID variable to form "Merged Data with Weights (Online Analysis Only)" (Dataset 4) for online analysis capabilities. MIDUS also maintains a Colectica portal, which allows users to interact with variables across waves and create customized subsets. Registration is required. ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection: Created online analysis version with question text.; Performed recodes and/or calculated derived variables.; Checked for undocumented or out-of-range codes.. Presence of Common Scales: Generalized Anxiety Disorder (GAD) Scale; Somatic Amplification Scale; The Alcohol Screening Test; The Conflict Tactics (CT) Scales; The Revised Conflict Tactics Scales (CTS2); Loyola Generativity Scale (LGS); Many scales were constructed for use in the Midlife in the United States (MIDUS 1), 1995-1996 Study. For additional information on scale construction and sources, please refer to the scale documentation included with the data collection. Respondents were drawn from a nationally representative random-digit-dial sample of non-institutionalized, English-speaking adults, aged 25-74, selected from working telephone banks in the coterminous United States. Those queried participated in an initial telephone interview and responded to a mail questionnaire. Please see the Descriptions of Midlife in the United Sates (MIDUS) Samples documentation provided by ICPSR for more detailed information. Respondents were drawn from a nationally representative random-digit-dial sample of non-institutionalized, English-speaking adults, aged 25-74, selected from working telephone banks in the coterminous United States. Those queried participated in an initial telephone interview and responded to a mail questionnaire. Smallest Geographic Unit: None Datasets: DS0: Study-Level Files DS1: Main, Siblings and Twin Data DS2: Twin Screener Data DS3: Coded Text Data DS4: Merged Data with Weights (Online Analysis Only) DS6: Midlife in the United States (MIDUS 1), 1995-1996, Merged Data with Weights (Online Analysis Only) Response Rates: The response rate for the national Random-Digit Dialing (RDD) sample was 70 percent. The Self-Administered Questionnaire (SAQ) follow-up response rate was 89 percent. computer-assisted telephone interview (CATI) Midlife in the United States (MIDUS) Series self-enumerated questionnaire mail questionnaire
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For further information contact us at helpdesk@openaire.eu33 citations 33 popularity Top 10% influence Top 10% impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection 2022Publisher:figshare Funded by:EC | COGS, NIH | Shared Genomic Segment An..., NIH | Understanding Ethnic Diff... +4 projectsEC| COGS ,NIH| Shared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa Pedigrees ,NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,EC| BRIDGES ,NWO| BBMRI-NL ,NIH| Breast Cancer Family Registry Cohort ,EC| B-CASTGiardiello, Daniele; Hooning, Maartje J.; Hauptmann, Michael; Keeman, Renske; Heemskerk-Gerritsen, B. A. M.; Becher, Heiko; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Camp, Nicola J.; Czene, Kamila; Devilee, Peter; Eccles, Diana M.; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; García-Closas, Montserrat; Haiman, Christopher A.; Hamann, Ute; Hopper, John L.; Jakubowska, Anna; Leeuwen, Floor E.; Lindblom, Annika; Lubiński, Jan; Margolin, Sara; Martinez, Maria Elena; Nevanlinna, Heli; Nevelsteen, Ines; Pelders, Saskia; Pharoah, Paul D. P.; Siesling, Sabine; Southey, Melissa C.; van der Hout, Annemieke H.; van Hest, Liselotte P.; Chang-Claude, Jenny; Hall, Per; Easton, Douglas F.; Steyerberg, Ewout W.; Schmidt, Marjanka K.;Abstract Background Prediction of contralateral breast cancer (CBC) risk is challenging due to moderate performances of the known risk factors. We aimed to improve our previous risk prediction model (PredictCBC) by updated follow-up and including additional risk factors. Methods We included data from 207,510 invasive breast cancer patients participating in 23 studies. In total, 8225 CBC events occurred over a median follow-up of 10.2 years. In addition to the previously included risk factors, PredictCBC-2.0 included CHEK2 c.1100delC, a 313 variant polygenic risk score (PRS-313), body mass index (BMI), and parity. Fine and Gray regression was used to fit the model. Calibration and a time-dependent area under the curve (AUC) at 5 and 10 years were assessed to determine the performance of the models. Decision curve analysis was performed to evaluate the net benefit of PredictCBC-2.0 and previous PredictCBC models. Results The discrimination of PredictCBC-2.0 at 10 years was higher than PredictCBC with an AUC of 0.65 (95% prediction intervals (PI) 0.56–0.74) versus 0.63 (95%PI 0.54–0.71). PredictCBC-2.0 was well calibrated with an observed/expected ratio at 10 years of 0.92 (95%PI 0.34–2.54). Decision curve analysis for contralateral preventive mastectomy (CPM) showed the potential clinical utility of PredictCBC-2.0 between thresholds of 4 and 12% 10-year CBC risk for BRCA1/2 mutation carriers and non-carriers. Conclusions Additional genetic information beyond BRCA1/2 germline mutations improved CBC risk prediction and might help tailor clinical decision-making toward CPM or alternative preventive strategies. Identifying patients who benefit from CPM, especially in the general breast cancer population, remains challenging.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 2022Publisher:figshare Funded by:EC | COGS, NIH | Shared Genomic Segment An..., NIH | Understanding Ethnic Diff... +4 projectsEC| COGS ,NIH| Shared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa Pedigrees ,NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,EC| BRIDGES ,NIH| Breast Cancer Family Registry Cohort ,EC| B-CAST ,NWO| BBMRI-NLGiardiello, Daniele; Hooning, Maartje J.; Hauptmann, Michael; Keeman, Renske; Heemskerk-Gerritsen, B. A. M.; Becher, Heiko; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Camp, Nicola J.; Czene, Kamila; Devilee, Peter; Eccles, Diana M.; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; García-Closas, Montserrat; Haiman, Christopher A.; Hamann, Ute; Hopper, John L.; Jakubowska, Anna; Leeuwen, Floor E.; Lindblom, Annika; Lubiński, Jan; Margolin, Sara; Martinez, Maria Elena; Nevanlinna, Heli; Nevelsteen, Ines; Pelders, Saskia; Pharoah, Paul D. P.; Siesling, Sabine; Southey, Melissa C.; van der Hout, Annemieke H.; van Hest, Liselotte P.; Chang-Claude, Jenny; Hall, Per; Easton, Douglas F.; Steyerberg, Ewout W.; Schmidt, Marjanka K.;Additional file 1: Table S3. Patient and primary breast cancer characteristics per study.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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Research data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:EC | ERAS, NWO | Evolution of astronomical..., EC | EARTHSEQUENCINGEC| ERAS ,NWO| Evolution of astronomically paced climate changes from Greenhouse to Icehouse world ,EC| EARTHSEQUENCINGBeddow, Helen M; Liebrand, Diederik; Wilson, Douglas S; Hilgen, Frederik J; Sluijs, Appy; Wade, Bridget S; Lourens, Lucas Joost;Astronomical tuning of sediment sequences requires both unambiguous cycle-pattern recognition in climate proxy records and astronomical solutions, and independent information about the phase relationship between these two. Here we present two different astronomically tuned age models for the Oligocene-Miocene Transition (OMT) from Integrated Ocean Drilling Program Site U1334 (equatorial Pacific Ocean) to assess the effect tuning has on astronomically calibrated ages and the geologic time scale. These alternative age models (from ~22 to ~24 Ma) are based on different tunings between proxy records and eccentricity: the first age model is based on an aligning CaCO3 weight (wt%) to Earth's orbital eccentricity, the second age model is based on a direct age calibration of benthic foraminiferal stable carbon isotope ratios (d13C) to eccentricity. To independently test which tuned age model and associated tuning assumptions is in best agreement with independent ages based on tectonic plate-pair spreading rates, we assign our tuned ages to the magnetostratigraphic reversals identified in deep-marine magnetic anomaly profiles. Subsequently, we compute tectonic plate-pair spreading rates based on the tuned ages. The resultant, alternative spreading rate histories indicate that the CaCO3 tuned age model is most consistent with a conservative assumption of constant, or linearly changing, spreading rates. The CaCO3 tuned age model thus provides robust ages and durations for polarity chrons C6Bn.1n-C6Cn.1r, which are not based on astronomical tuning in the latest iteration of the Geologic Time Scale. Furthermore, it provides independent evidence that the relatively large (several 10,000 years) time lags documented in the benthic foraminiferal isotope records relative to orbital eccentricity, constitute a real feature of the Oligocene-Miocene climate system and carbon cycle. The age constraints from Site U1334 thus provide independent evidence that the delayed responses of the Oligocene-Miocene climate-cryosphere system and carbon cycle resulted from highly nonlinear feedbacks to astronomical forcing. Supplement to: Beddow, Helen M; Liebrand, Diederik; Wilson, Douglas S; Hilgen, Frederik J; Sluijs, Appy; Wade, Bridget S; Lourens, Lucas Joost (2018): Astronomical tunings of the Oligocene-Miocene transition from Pacific Ocean Site U1334 and implications for the carbon cycle. Climate of the Past, 14(3), 255-270
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:NWO | Evolution of astronomical..., UKRI | The paradox of high-ampli..., EC | EARTHSEQUENCINGNWO| Evolution of astronomically paced climate changes from Greenhouse to Icehouse world ,UKRI| The paradox of high-amplitude inter(glacial) variability across the Oligo-Miocene transition tackled using spectacular new deep-sea sediment archives ,EC| EARTHSEQUENCINGLiebrand, Diederik; Raffi, Isabella; Fraguas, Ángela; Laxenaire, Rémi; Bosmans, Joyce H C; Hilgen, Frederik J; Wilson, Paul A; Batenburg, Sietske J; Beddow, Helen M; Bohaty, Steven M; Bown, Paul R; Crocker, Anya J; Huck, Claire E; Lourens, Lucas Joost; Sabia, Luciana;Pelagic sediments from the subtropical South Atlantic Ocean contain geographically extensive Oligocene ooze and chalk layers that consist almost entirely of the calcareous nannofossil Braarudosphaera. Poor recovery and the lack of precise dating of these horizons in previous studies has limited our understanding of the exact number of acmes, their timing and durations, and the causes of their recurrence. Here we present a high-resolution, astronomically tuned stratigraphy of Braarudosphaera oozes (29.5-27.9 Ma) from Ocean Drilling Program Site 1264 in the subtropical southeastern Atlantic Ocean. We identify seven acme events in the Braarudosphaera abundance record. The longest lasting acme event corresponds to a strong minimum in the ~2.4-My eccentricity cycle, and four acme events coincide with ~110-ky and 405-ky eccentricity maxima. We propose that eccentricity-modulated precession forcing of the freshwater budget of the South Atlantic Ocean resulted in the episodic formation of a shallow pycnocline and hyperstratification of the upper water column. We speculate that stratified surface water conditions may have served as a virtual sea floor, which facilitated the widespread Braarudosphaera acmes. This explanation reconciles the contrasting distribution patterns of Braarudosphaera in the modern ocean, limited largely to shallow water coastal settings, compared to their relatively brief and expanded oceanic distribution in the past. Supplement to: Liebrand, Diederik; Raffi, Isabella; Fraguas, Ángela; Laxenaire, Rémi; Bosmans, Joyce H C; Hilgen, Frederik J; Wilson, Paul A; Batenburg, Sietske J; Beddow, Helen M; Bohaty, Steven M; Bown, Paul R; Crocker, Anya J; Huck, Claire E; Lourens, Lucas Joost; Sabia, Luciana (2018): Orbitally Forced Hyperstratification of the Oligocene South Atlantic Ocean. Paleoceanography and Paleoclimatology, 33(5), 511-529
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.878110&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.878110&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Other dataset type , Dataset 2018 EnglishPublisher:PANGAEA Funded by:EC | SINK, NWO | Subduction Initiation rec...EC| SINK ,NWO| Subduction Initiation reconstructed from Neotethyan Kinematics (SINK): An integrated geological and numerical study of the driving forces behind plate tectonicsGürer, Derya; van Hinsbergen, Douwe J J; Özkaptan, Murat; Creton, Iverna; Koymans, Mathijs R; Cascella, Antonio; Langereis, Cornelis G;To quantitatively reconstruct the kinematic evolution of Central and Eastern Anatolia within the framework of Neotethyan subduction accommodating Africa-Eurasia convergence, we paleomagnetically assess timing and amount of vertical axis rotations across the Ulukisla and Sivas regions. We show paleomagnetic results from ~30 localities identifying a coherent rotation of a block - comprising the southern Kirsehir Block, the Ulukisla basin, the Central and Eastern Taurides, and the southern part of the Sivas basin. This block experienced a ~30° counter-clockwise vertical axis rotation since Oligocene time. Sediments in the northern Sivas region show clockwise rotations. We use the rotation patterns together with known fault zones to argue that the counter-clockwise rotating domain of south-central Turkey was bounded by the Savcili Thrust Zone and Deliler-Tecer Fault Zone in the north and by the African-Arabian trench in the south, the western boundary of which is poorly constrained and requires future study. Our new paleomagnetic constraints provide a key ingredient for future kinematic restorations of the Anatolian tectonic collage. We combine our extensive new dataset with existing data (Guerer et al., 2018, and references therein) to identify the dimension of rotating domains in Central and Eastern Anatolia, and identify structures that may have accommodated these rotations. Paleomagnetic interpretations and statistical analyses were carried out using the platform independent portal Paleomagnetism.org (Koymans et al., 2016). Supplement to: Gürer, Derya; van Hinsbergen, Douwe J J; Özkaptan, Murat; Creton, Iverna; Koymans, Mathijs R; Cascella, Antonio; Langereis, Cornelis G (2018): Paleomagnetic constraints on the timing and distribution of Cenozoic rotations in Central and Eastern Anatolia. Solid Earth, 9(2), 295-322
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceOther dataset type . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.887421&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu1 citations 1 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceOther dataset type . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.887421&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2011 EnglishPublisher:PANGAEA Funded by:EC | DINOPRO, NWO | Biotic, climatic and geoc..., EC | PACEMAKEREC| DINOPRO ,NWO| Biotic, climatic and geochemical change during Early Eocene transient global warming events ,EC| PACEMAKERSluijs, Appy; Bijl, Peter K; Schouten, Stefan; Röhl, Ursula; Reichart, Gert-Jan; Brinkhuis, Henk;A brief (~150 kyr) period of widespread global average surface warming marks the transition between the Paleocene and Eocene epochs, ~56 million years ago. This so-called "Paleocene-Eocene thermal maximum" (PETM) is associated with the massive injection of 13C-depleted carbon, reflected in a negative carbon isotope excursion (CIE). Biotic responses include a global abundance peak (acme) of the subtropical dinoflagellate Apectodinium. Here we identify the PETM in a marine sedimentary sequence deposited on the East Tasman Plateau at Ocean Drilling Program (ODP) Site 1172 and show, based on the organic paleothermometer TEX86, that southwest Pacific sea surface temperatures increased from ~26 °C to ~33°C during the PETM. Such temperatures before, during and after the PETM are >10 °C warmer than predicted by paleoclimate model simulations for this latitude. In part, this discrepancy may be explained by potential seasonal biases in the TEX86 proxy in polar oceans. Additionally, the data suggest that not only Arctic, but also Antarctic temperatures may be underestimated in simulations of ancient greenhouse climates by current generation fully coupled climate models. An early influx of abundant Apectodinium confirms that environmental change preceded the CIE on a global scale. Organic dinoflagellate cyst assemblages suggest a local decrease in the amount of river run off reaching the core site during the PETM, possibly in concert with eustatic rise. Moreover, the assemblages suggest changes in seasonality of the regional hydrological system and storm activity. Finally, significant variation in dinoflagellate cyst assemblages during the PETM indicates that southwest Pacific climates varied significantly over time scales of 103 - 104 years during this event, a finding comparable to similar studies of PETM successions from the New Jersey Shelf. Supplement to: Sluijs, Appy; Bijl, Peter K; Schouten, Stefan; Röhl, Ursula; Reichart, Gert-Jan; Brinkhuis, Henk (2011): Southern ocean warming, sea level and hydrological change during the Paleocene-Eocene thermal maximum. Climate of the Past, 7(1), 47-61
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceDataset . Collection . 2011License: CC BYPANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2011License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.756399&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceDataset . Collection . 2011License: CC BYPANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2011License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.756399&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:NWO | Perturbations of System E..., EC | DIOLSNWO| Perturbations of System Earth: Reading the Past to Project the Future - A proposal to create the Netherlands Earth System Science Centre (ESSC) ,EC| DIOLSde Bar, Marijke W; Stolwijk, Dave; McManus, Jerry F; Sinninghe Damsté, Jaap S; Schouten, Stefan;In this study we have applied different indices based on long chain diols, i.e., the Long chain Diol Index (LDI) as proxy for past SST, the Diol Index as indicator of past upwelling conditions and the Nutrient Diol Index (NDI) as proxy for nitrate and phosphate concentrations in seawater. The proxies were analyzed in marine sediments recovered at ODP Site 1234, located within the Peru-Chile upwelling system, with a 2 kyr resolution, covering the last 150 kyrs. We also generated TEX^H^~86 and U_K'37 temperature and planktonic δ^18^O records, as well as total organic carbon (TOC) and accumulation rates (ARs) of TOC and lipid biomarkers (i.e., C~37~ alkenones, GDGTs, dinosterol and loliolide) to reconstruct past phytoplankton production. The LDI-derived SST record co-varies with TEX^H^86- and UK'37-derived SST records as well as with the planktonic δ^18^O record, implying that the LDI reflects past SST variations at this site. TOC and phytoplankton AR records indicate increased export production during the Last Interglacial (MIS 5), simultaneous with a peak in the abundance of preserved _Chaetoceros diatoms, suggesting intensified upwelling during this period. The Diol Index is relatively low during the upwelling period, but peaks before and after this period, suggesting that Proboscia diatoms were more abundant before and after the period of upwelling. The NDI reveals the same trends as the Diol Index suggesting that the input of nitrate and phosphate was minimal during upwelling, which is unrealistic. We suggest that the Diol Index and NDI should perhaps be considered as indicators for Proboscia productivity instead of upwelling conditions or nutrient concentrations. Supplement to: de Bar, Marijke W; Stolwijk, Dave; McManus, Jerry F; Sinninghe Damsté, Jaap S; Schouten, Stefan (2018): A Late Quaternary climate record based on long-chain diol proxies from the Chilean margin. Climate of the Past, 14(11), 1783-1803
PANGAEA arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.892652&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.892652&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection , Dataset 2018 EnglishPublisher:PANGAEA Funded by:NWO | A sensitive ultra high pr..., EC | DINOPRONWO| A sensitive ultra high pressure liquid chromatography - mass spectrometer to unlock high-resolution climate archives ,EC| DINOPROFrieling, Joost; Reichart, Gert-Jan; Middelburg, Jack J; Röhl, Ursula; Westerhold, Thomas; Bohaty, Steven M; Sluijs, Appy;The Paleocene - Eocene Thermal Maximum (PETM; 56 Ma) was a phase of rapid global warming associated with massive carbon input into the ocean-atmosphere system from a 13C-depleted reservoir. Many mid- and high-latitude sections have been studied and document changes in salinity, hydrology and sedimentation, deoxygenation, biotic overturning and migrations, but detailed records from tropical regions are lacking. Here, we study the PETM at Ocean Drilling Program (ODP) Site 959 in the equatorial Atlantic using a range of organic and inorganic proxies and couple these with dinoflagellate cyst (dinocyst) assemblage analysis. The PETM at Site 959 was previously found to be marked by a ~3.8 per mil negative carbon isotope excursion (CIE), and a ~4 ºC surface ocean warming from the uppermost Paleocene to peak PETM, of which ~1 ºC occurs before the onset of the CIE. We record upper Paleocene dinocyst assemblages that are similar to PETM assemblages as found in extra-tropical regions, confirming poleward migrations of ecosystems during the PETM. The early stages of the PETM are marked by a typical acme of the tropical genus Apectodinium, which reaches abundances of up to 95 %. Subsequently, dinocyst abundances diminish greatly, as do carbonate and pyritized silicate microfossils. The combined paleoenvironmental information from Site 959 and a close by shelf site in Nigeria implies the general absence of eukaryotic surface-dwelling microplankton during peak PETM warmth is most likely caused by heat stress. Crucially, abundant organic benthic foraminiferal linings imply sustained export production, likely driven by prokaryotes. In sharp contrast, the recovery of the CIE yields rapid (<<10 kyr) fluctuations in the abundance of several dinocyst groups, suggesting extreme ecosystem and environmental variability. Supplement to: Frieling, Joost; Reichart, Gert-Jan; Middelburg, Jack J; Röhl, Ursula; Westerhold, Thomas; Bohaty, Steven M; Sluijs, Appy (2018): Tropical Atlantic climate and ecosystem regime shifts during the Paleocene-Eocene Thermal Maximum. Climate of the Past, 14(1), 39-55
PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.884760&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert PANGAEA - Data Publi... arrow_drop_down PANGAEA - Data Publisher for Earth and Environmental ScienceCollection . 2018License: CC BYData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1594/pangaea.884760&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 2022Publisher:figshare Funded by:EC | COGS, NWO | BBMRI-NL, EC | BRIDGES +4 projectsEC| COGS ,NWO| BBMRI-NL ,EC| BRIDGES ,NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,NIH| Shared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa Pedigrees ,NIH| Breast Cancer Family Registry Cohort ,EC| B-CASTGiardiello, Daniele; Hooning, Maartje J.; Hauptmann, Michael; Keeman, Renske; Heemskerk-Gerritsen, B. A. M.; Becher, Heiko; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Camp, Nicola J.; Czene, Kamila; Devilee, Peter; Eccles, Diana M.; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; García-Closas, Montserrat; Haiman, Christopher A.; Hamann, Ute; Hopper, John L.; Jakubowska, Anna; Leeuwen, Floor E.; Lindblom, Annika; Lubiński, Jan; Margolin, Sara; Martinez, Maria Elena; Nevanlinna, Heli; Nevelsteen, Ines; Pelders, Saskia; Pharoah, Paul D. P.; Siesling, Sabine; Southey, Melissa C.; van der Hout, Annemieke H.; van Hest, Liselotte P.; Chang-Claude, Jenny; Hall, Per; Easton, Douglas F.; Steyerberg, Ewout W.; Schmidt, Marjanka K.;Additional file 2: Table S1. Description of the studies included in the analyses.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 1999 EnglishPublisher:Inter-university Consortium for Political and Social Research (ICPSR) Funded by:NIH | TRAINING IN RESEARCH ON M..., NIH | Midlife Health in Japan (..., AKA | Work stress and risk of c... +92 projectsNIH| TRAINING IN RESEARCH ON MENTAL HEALTH AND AGING ,NIH| Midlife Health in Japan (MIDJA) and the U.S. (MIDUS) ,AKA| Work stress and risk of coronary heart disease: Does a healthy life style eliminate the adverse effect? Pooled analysis of 6 major prospective cohort studies from Europe ,NHMRC| The Older Australian Twins Study (OATS) of healthy brain ageing and age-related neurocognitive disorders ,NIH| Daily Stress and Well-Being during Adulthood ,CIHR ,NIH| SOCIAL AND OCCUPATIONAL INFLUENCES ON HEALTH AND ILLNESS ,AKA| Oxygenology of soil ,NIH| Gene-Environment Interplay of Social Contexts and Aging-Related Outcomes ,NIH| Postdoctoral Training in Geriatric Psychiatry Research ,NIH| ORIGINS OF VARIANCE IN THE OLD-OLD: OCTOGENARIAN TWINS ,NIH| Self-regulation as a Health-Protective Factor in Adverse Socioeconomic Conditions ,NIH| Health behaviors over the adult lifecourse and cognitive aging ,NIH| GENETIC &ENVIRONMENTAL INFLUENCES--BIOBEHAVIORAL AGING ,NIH| Sexuality, Aging and Heart Disease: Translating from Population to Patient ,NIH| Wisconsin Longitudinal Study: Tracking the Life Course ,NIH| OLDEST-OLD MORTALITY AND DISABILITY AMONG DANISH TWINS ,NIH| Stress, Aging and Working Memory ,NIH| CONTROL BELIEFS, MEMORY, AND AGING ,NIH| Biological Embedding of Early-Life SES ,UKRI| Offshore Platform for Energy Competitiveness (OPEC) ,AKA| Genomic epidemiology of addictions and their consequences - national, Nordic and international dimensions. ,AKA| Work, well-being and health - a life course perspective: British arm of Academy of Finland consortia 10190 and 10187 / Consortium: ELRFWCDD ,AKA| Genomic epidemiology of addictions and their consequences - national, Nordic and international dimensions ,NIH| Sleep and Divorce: Identifying Bidirectional Vulnerability and Resilience ,NIH| CTSA INFRASTRUCTURE FOR CLINICAL TRIALS ,NIH| Sex differences in the relationship between APOE and AD: Role of sexual differentiation ,NIH| GENETIC AND ENVIRONMENTAL INFLUENCES IN BEHAVIORAL AGING ,NIH| SES health gradients in late life: testing models of gene-environment interplay in an international twin consortium ,NIH| Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortium ,NIH| Risk for Alzheimer's Disease and Cognitive Decline in Project TALENT ,NIH| Optimizing Couple-Oriented Interventions for Chronic Illness ,NIH| Implementing World Health Assembly Resolution 60.26 ???Workers' Health: Global Pl ,ARC| Discovery Projects - Grant ID: DP200100876 ,AKA| Center of Excellence in Complex Disease Genetics-from Discovery to Precision Medicine / Consortium: CoECDG ,NIH| Integrative Pathways to Health and Illness ,NIH| Personality and Well-Being Trajectories in Adulthood ,NIH| CHANGES IN HEALTH--SOCIOECONOMIC STATUS AND PATHWAYS ,NIH| 1995 SUMMER INSTITUTE IN GERIATRIC MEDICINE ,NIH| AGING AND INTRAINDIVIDUAL COGNITIVE VARIABILITY ,NIH| CORE--PROGRAM DEVELOPMENT ,NHMRC| Gene-environment interaction in healthy brain ageing and age related neurodegeneration ,AKA| Center of Excellence in Complex Disease Genetics ,NIH| DEMOGRAPHY ,NIH| Integrative Pathways to Health and Illness ,SSHRC ,AKA| CoE in Complex Disease Genetics ,NIH| Integrative Analysis of Change in Cognition and Health ,NIH| UCLA OLDER AMERICANS INDEPENDENCE CENTER ,NHMRC| Australian Centre of Excellence in Twin Research ,NHMRC| The genetic and environmental determinants of amyloid deposition in older individuals: an amyloid imaging study using the twin design ,NIH| The VETSA Longitudinal MRI Twin Study of Aging ,AKA| Determinants of Early Exit from Work Force: An International Multicohort Study. ,NIH| Daily stressor reactivity and profiles of physical health across adulthood ,NIH| Genes, Enivronment and the Adjustment of Family Members ,AKA| Determinants of labour market participation and prognosis of common chronic diseases in working populations: a study of cohorts in Finland, United Kingdom and France ,NSF| IBSS: Understanding Long-Term Effects on Children in Economic Distress ,AKA| Heterogeneity of depression at symptom level: Specific versus general patterns in etiology, development, and disability ,NIH| Infrastructure for the Office of Population Research ,NIH| Histories of Social Engagement and Cognitive Functioning ,NIH| Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African Americans ,NIH| WISCONSIN LONGITUDINAL STUDY ,EC| ENGAGE ,NIH| The Population Research Institute ,NWO| Genetische en omgevingsinvloeden op psychopathologie en geluk tijdens de adolescentie ,NIH| TWIN STUDY OF NORMAL AGING ,AKA| Midlife predictors of dementia, frailty and disability at older ages ,NIH| A Longitudinal Twin Study of Cognition and Personality ,NIH| Biopsychosocial Pathways to Type 2 Diabetes ,NIH| Integrative Pathways to Health and Illness ,NWO| A Twin-sibling Study of Adolescent Wellness ,NIH| The VETSA Longitudinal Twin Study of Cortisol and Aging ,NIH| Informing anti-tobacco communications with affective and decision science: Application of the Appraisal Tendency Framework ,NIH| The Greatest Generation: The NAS-NRC WWII Twin Registry as a Scientific Resource ,NIH| A 55-Year Follow-up Study of Project TALENT Twins and Siblings ,AKA| Genetic and environmental predictors of tobacco, drug and alcohol addiction in adolescence and young adulthood ¿ a lifecourse twin and population approach / Consortium: addictgene ,NIH| Aging, Emotional Well-being, and Physical Health ,NIH| AGING AND HEALTH TRAJECTORIES AMONG BLACK &WHITE ADULTS ,NIH| GCRC ,NIH| MEASUREMENT OF ESTRADIOL AND OTHER RELATED HORMONES BY TANDEM MASS SPECTROSCOPY ,NIH| Social Regulation of Gene Expression ,NIH| HEALTH AND PSYCHOSOCIAL FACTORS IN OLDER BLACK TWINS ,UKRI| RootDetect: Remote Detection and Precision Management of Root Health ,NIH| A Longitudinal Twin Study of Cognition and Aging ,NIH| Social and Economic Analysis of Demographic Change ,NIH| Research Training Program in the Behavioral and Biomedical Sciences ,UKRI| Centre for Cognitive Ageing & Cognitive Epidemiology ,AKA| Determinants of labour market participation and prognosis of common chronic diseases in working populations: a study of cohorts in Finland, United Kingdom and France ,AKA| Indicators of marginalization - Role of cognition, substance use and mental health disorders: Longitudinal studies from childhood to end of adolescence ,NIH| Causal Effects of Schooling on Adult and Child Health ,NIH| Institutional Clinical and Translational Science Award ,NIH| Genetic Moderators of Divorce Adjustment: A Pilot Investigation ,NIH| Bio-social Determinants of Fertility &Related Behaviors ,NIH| IMSD Program at Wayne State University ,AKA| Predictors, neuropsychological correlates, and consequences of cannabis and alcohol use among Finnish young adults. A twin and population approachBrim, Orville Gilbert; Baltes, Paul B.; Bumpass, Larry L.; Cleary, Paul D.; Featherman, David L.; Hazzard, William R.; Kessler, Ronald C.; Lachman, Margie E.; Markus, Hazel Rose; Marmot, Michael G.; Rossi, Alice S.; Ryff, Carol D.; Shweder, Richard A.;doi: 10.3886/icpsr02760.v11 , 10.3886/icpsr02760.v1 , 10.3886/icpsr02760.v17 , 10.3886/icpsr02760.v5 , 10.3886/icpsr02760.v10 , 10.3886/icpsr02760.v19 , 10.3886/icpsr02760.v14 , 10.3886/icpsr02760.v7 , 10.3886/icpsr02760.v8 , 10.3886/icpsr02760.v16 , 10.3886/icpsr02760.v12 , 10.3886/icpsr02760.v4 , 10.3886/icpsr02760.v13 , 10.3886/icpsr02760.v6 , 10.3886/icpsr02760.v3 , 10.3886/icpsr02760.v18 , 10.3886/icpsr02760.v15 , 10.3886/icpsr02760.v2 , 10.3886/icpsr02760.v9 , 10.3886/icpsr02760
doi: 10.3886/icpsr02760.v11 , 10.3886/icpsr02760.v1 , 10.3886/icpsr02760.v17 , 10.3886/icpsr02760.v5 , 10.3886/icpsr02760.v10 , 10.3886/icpsr02760.v19 , 10.3886/icpsr02760.v14 , 10.3886/icpsr02760.v7 , 10.3886/icpsr02760.v8 , 10.3886/icpsr02760.v16 , 10.3886/icpsr02760.v12 , 10.3886/icpsr02760.v4 , 10.3886/icpsr02760.v13 , 10.3886/icpsr02760.v6 , 10.3886/icpsr02760.v3 , 10.3886/icpsr02760.v18 , 10.3886/icpsr02760.v15 , 10.3886/icpsr02760.v2 , 10.3886/icpsr02760.v9 , 10.3886/icpsr02760
The Midlife in the United States (MIDUS) is a collaborative, interdisciplinary investigation of patterns, predictors, and consequences of midlife development in the areas of physical health, psychological well-being, and social responsibility. A description of the study and findings from it are available at http://www.midus.wisc.edu. The first wave of the MIDUS study (MIDUS 1 or M1) collected survey data from a total of 7,108 participants. The baseline sample was comprised of individuals from four subsamples: (1) a national RDD (random digit dialing) sample (n=3,487); (2) oversamples from five metropolitan areas in the U.S. (n=757); (3) siblings of individuals from the RDD sample (n=950); and (4) a national RDD sample of twin pairs (n=1,914). All eligible participants were non-institutionalized, English-speaking adults in the coterminous United States, aged 25 to 74. Data from the samples were collected primarily in 1995/96. The survey (Project 1) dataset contains responses from a 30-minute Phone interview and two 50-page Self-Administered Questionnaire (SAQ) instruments. Of the 7,108 respondents who completed the Phone interview, 6,325 also completed the SAQ. This updated version of the study is comprised of three primary datasets: Dataset 1, Main, Siblings, and Twin Data, contains responses from the main survey of 7,108 respondents. Respondents were asked to provide extensive information on their physical and mental health throughout their adult lives, and to assess the ways in which their lifestyles, including relationships and work-related demands, contributed to the conditions experienced. Those queried were asked to describe their histories of physical ailments, including heart-related conditions and cancer, as well as the treatment and/or lifestyle changes they went through as a result. A series of questions addressed alcohol, tobacco, and illegal drug use, and focused on history of use, regularity of use, attempts to quit, and how the use of those substances affected respondents' physical and mental well-being. Additional questions addressed respondents' sense of control over their health, their awareness of changes in their medical conditions, commitment to regular exercise and a healthy diet, experience with menopause, the decision-making process used to deal with health concerns, experiences with nontraditional remedies or therapies, and history of attending support groups. Respondents were asked to compare their overall well-being with that of their peers and to describe social, physical, and emotional characteristics typical of adults in their 20's, 40's, and 60's. Information on the work histories of respondents and their significant others was also elicited, with items covering the nature of their occupations, work-related physical and emotional demands, and how their personal health had correlated to their jobs. An additional series of questions focusing on childhood queried respondents regarding the presence/absence of their parents, religion, rules/punishments, love/affection, physical/verbal abuse, and the quality of their relationships with their parents and siblings. Respondents were also asked to consider their personal feelings of accomplishment, desire to learn, sense of control over their lives, interests, and hopes for the future. The Datasets previously numbered 2 and 3 have been removed to avoid redundancies, and all datasets have been renumbered. Please refer to the readme file. Dataset 2, Twin Screener Data, provides the first national sample of twin pairs ascertained randomly via the telephone. Dataset 3, Coded Text Responses, describes how open-ended textual responses in the MIDUS 1 Computer-Assisted Telephone Interview (CATI) and Self-Administered Questionnaire (SAQ) were transformed into categorical numeric codes. These codes are included in a stand-alone dataset containing only those cases (N=3,950) that contained text data in their responses. Online Analysis Only: Datasets 1, 2, and 3 were merged together by the SU_ID variable to form "Merged Data with Weights (Online Analysis Only)" (Dataset 4) for online analysis capabilities. MIDUS also maintains a Colectica portal, which allows users to interact with variables across waves and create customized subsets. Registration is required. ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection: Created online analysis version with question text.; Performed recodes and/or calculated derived variables.; Checked for undocumented or out-of-range codes.. Presence of Common Scales: Generalized Anxiety Disorder (GAD) Scale; Somatic Amplification Scale; The Alcohol Screening Test; The Conflict Tactics (CT) Scales; The Revised Conflict Tactics Scales (CTS2); Loyola Generativity Scale (LGS); Many scales were constructed for use in the Midlife in the United States (MIDUS 1), 1995-1996 Study. For additional information on scale construction and sources, please refer to the scale documentation included with the data collection. Respondents were drawn from a nationally representative random-digit-dial sample of non-institutionalized, English-speaking adults, aged 25-74, selected from working telephone banks in the coterminous United States. Those queried participated in an initial telephone interview and responded to a mail questionnaire. Please see the Descriptions of Midlife in the United Sates (MIDUS) Samples documentation provided by ICPSR for more detailed information. Respondents were drawn from a nationally representative random-digit-dial sample of non-institutionalized, English-speaking adults, aged 25-74, selected from working telephone banks in the coterminous United States. Those queried participated in an initial telephone interview and responded to a mail questionnaire. Smallest Geographic Unit: None Datasets: DS0: Study-Level Files DS1: Main, Siblings and Twin Data DS2: Twin Screener Data DS3: Coded Text Data DS4: Merged Data with Weights (Online Analysis Only) DS6: Midlife in the United States (MIDUS 1), 1995-1996, Merged Data with Weights (Online Analysis Only) Response Rates: The response rate for the national Random-Digit Dialing (RDD) sample was 70 percent. The Self-Administered Questionnaire (SAQ) follow-up response rate was 89 percent. computer-assisted telephone interview (CATI) Midlife in the United States (MIDUS) Series self-enumerated questionnaire mail questionnaire
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For further information contact us at helpdesk@openaire.eu33 citations 33 popularity Top 10% influence Top 10% impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Collection 2022Publisher:figshare Funded by:EC | COGS, NIH | Shared Genomic Segment An..., NIH | Understanding Ethnic Diff... +4 projectsEC| COGS ,NIH| Shared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa Pedigrees ,NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,EC| BRIDGES ,NWO| BBMRI-NL ,NIH| Breast Cancer Family Registry Cohort ,EC| B-CASTGiardiello, Daniele; Hooning, Maartje J.; Hauptmann, Michael; Keeman, Renske; Heemskerk-Gerritsen, B. A. M.; Becher, Heiko; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Camp, Nicola J.; Czene, Kamila; Devilee, Peter; Eccles, Diana M.; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; García-Closas, Montserrat; Haiman, Christopher A.; Hamann, Ute; Hopper, John L.; Jakubowska, Anna; Leeuwen, Floor E.; Lindblom, Annika; Lubiński, Jan; Margolin, Sara; Martinez, Maria Elena; Nevanlinna, Heli; Nevelsteen, Ines; Pelders, Saskia; Pharoah, Paul D. P.; Siesling, Sabine; Southey, Melissa C.; van der Hout, Annemieke H.; van Hest, Liselotte P.; Chang-Claude, Jenny; Hall, Per; Easton, Douglas F.; Steyerberg, Ewout W.; Schmidt, Marjanka K.;Abstract Background Prediction of contralateral breast cancer (CBC) risk is challenging due to moderate performances of the known risk factors. We aimed to improve our previous risk prediction model (PredictCBC) by updated follow-up and including additional risk factors. Methods We included data from 207,510 invasive breast cancer patients participating in 23 studies. In total, 8225 CBC events occurred over a median follow-up of 10.2 years. In addition to the previously included risk factors, PredictCBC-2.0 included CHEK2 c.1100delC, a 313 variant polygenic risk score (PRS-313), body mass index (BMI), and parity. Fine and Gray regression was used to fit the model. Calibration and a time-dependent area under the curve (AUC) at 5 and 10 years were assessed to determine the performance of the models. Decision curve analysis was performed to evaluate the net benefit of PredictCBC-2.0 and previous PredictCBC models. Results The discrimination of PredictCBC-2.0 at 10 years was higher than PredictCBC with an AUC of 0.65 (95% prediction intervals (PI) 0.56–0.74) versus 0.63 (95%PI 0.54–0.71). PredictCBC-2.0 was well calibrated with an observed/expected ratio at 10 years of 0.92 (95%PI 0.34–2.54). Decision curve analysis for contralateral preventive mastectomy (CPM) showed the potential clinical utility of PredictCBC-2.0 between thresholds of 4 and 12% 10-year CBC risk for BRCA1/2 mutation carriers and non-carriers. Conclusions Additional genetic information beyond BRCA1/2 germline mutations improved CBC risk prediction and might help tailor clinical decision-making toward CPM or alternative preventive strategies. Identifying patients who benefit from CPM, especially in the general breast cancer population, remains challenging.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euResearch data keyboard_double_arrow_right Dataset 2022Publisher:figshare Funded by:EC | COGS, NIH | Shared Genomic Segment An..., NIH | Understanding Ethnic Diff... +4 projectsEC| COGS ,NIH| Shared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa Pedigrees ,NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,EC| BRIDGES ,NIH| Breast Cancer Family Registry Cohort ,EC| B-CAST ,NWO| BBMRI-NLGiardiello, Daniele; Hooning, Maartje J.; Hauptmann, Michael; Keeman, Renske; Heemskerk-Gerritsen, B. A. M.; Becher, Heiko; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Camp, Nicola J.; Czene, Kamila; Devilee, Peter; Eccles, Diana M.; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; García-Closas, Montserrat; Haiman, Christopher A.; Hamann, Ute; Hopper, John L.; Jakubowska, Anna; Leeuwen, Floor E.; Lindblom, Annika; Lubiński, Jan; Margolin, Sara; Martinez, Maria Elena; Nevanlinna, Heli; Nevelsteen, Ines; Pelders, Saskia; Pharoah, Paul D. P.; Siesling, Sabine; Southey, Melissa C.; van der Hout, Annemieke H.; van Hest, Liselotte P.; Chang-Claude, Jenny; Hall, Per; Easton, Douglas F.; Steyerberg, Ewout W.; Schmidt, Marjanka K.;Additional file 1: Table S3. Patient and primary breast cancer characteristics per study.
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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